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Merck

CYBB

cytochrome b-245, beta polypeptide

别名:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
物种:
UniProtKB ID:
基因ID:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)

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Antibodies

货号
说明
物种反应性
应用
Anti-CYBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-gp91-phox Antibody, Upstate®, from rabbit,
物种反应性
human
应用
western blot
Anti-gp91phox (NOX2) Antibody, ,
物种反应性
human
应用
flow cytometry
western blot
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rabbit, rat
应用
western blot
Anti-NOX2/gp91phox Antibody, clone 2Y8W3, Rabbit Monoclonal, ,
物种反应性
human, mouse, rat
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CYBB,
物种
human