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Merck

CILP

cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

别名:
CILP-1, HsT18872
物种:
UniProtKB ID:
基因ID:
  • Human(8483) Summary: Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]
  • Mouse(214425) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Rat(315761) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Zebrafish(553329) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • cow(100336614) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Horse(100053337) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • domestic cat(101084795) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • dog(487603) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • sheep(101119218) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • chicken(415533) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • naked mole-rat(101723750) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • domestic guinea pig(100721580) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

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ELISA

货号
说明
物种
人CILP-1 ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-CILP antibody produced in mouse, clone 2C5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-CILP antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Cilp,
物种
mouse
MISSION® esiRNA, targeting human CILP,
物种
human