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Merck

CBX5

chromobox homolog 5

别名:
HP1, HP1A
物种:
UniProtKB ID:
基因ID:
  • Human(23468) Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12419) chromobox 5
  • Rat(300266) chromobox homolog 5
  • sheep(100307036) chromobox homolog 5
  • naked mole-rat(101710464) chromobox homolog 5
  • domestic guinea pig(100727253) chromobox homolog 5
  • cow(538885) chromobox homolog 5
  • dog(477593) chromobox homolog 5
  • Zebrafish(563396) chromobox homolog 5 (HP1 alpha homolog, Drosophila)
  • domestic cat(101091461) chromobox homolog 5

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Antibodies

货号
说明
物种反应性
应用
抗异染色质蛋白-1α抗体,克隆2HP-1H5, ascites fluid, clone 2HP-1H5, Chemicon®,
物种反应性
human, mouse
应用
ELISA
immunocytochemistry

immunohistochemistry
抗-HP1α 抗体,克隆15.19s2, clone 15.19s2, Upstate®, from mouse,
物种反应性
human, mouse, vertebrates
应用
ChIP
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-CBX5 Antibody, clone 5I2-K ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-HP1 α antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-CBX5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Cbx5,
物种
mouse
MISSION® esiRNA, targeting human CBX5,
物种
human