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Merck

AKR1B1

aldo-keto reductase family 1, member B1 (aldose reductase)

别名:
ADR, ALDR1, ALR2, AR
物种:
UniProtKB ID:
基因ID:
  • Human(231) Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
  • Rat(24192) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Domestic Rabbit(100009122) aldo-keto reductase family 1, member B1 (aldose reductase)
  • naked mole-rat(101720124) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic guinea pig(100718017) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Zebrafish(415138) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic cat(101095406) aldo-keto reductase family 1, member B1 (aldose reductase)
  • cow(317748) aldo-keto reductase family 1, member B1 (aldose reductase)
  • dog(607537) aldo-keto reductase family 1, member B1 (aldose reductase)
  • sheep(101120824) aldo-keto reductase family 1, member B1 (aldose reductase)

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Antibodies

货号
说明
物种反应性
应用
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-AKR1B1 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
dog, human, mouse, pig, rat
应用
western blot
Anti-AKR1B1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
guinea pig, horse, human, mouse, rat
应用
immunohistochemistry
western blot
Anti-AKR1B1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
奎诺二甲基丙烯酸酯, 97%,
物种
rat
马尿酸, 98%,
物种
rat
芴-9-羧酸, 96%,
物种
rat
(±)-棉酚 来源于棉花种子, ≥95% (HPLC),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human AKR1B1,
物种
human