SRE0013
Interferon Alpha 2A human
recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE), lyophilized powder
Synonym(s):
Interferon α 2A human, INFα2A
Sign Into View Organizational & Contract Pricing
All Photos(3)
About This Item
UNSPSC Code:
41106305
NACRES:
NA.26
Pricing and availability is not currently available.
Recommended Products
recombinant
expressed in HEK 293 cells
Quality Level
Assay
≥98% (SDS-PAGE)
form
lyophilized powder
storage temp.
−20°C
Looking for similar products? Visit Product Comparison Guide
General description
IFN-α-2a belongs to the type I interferon protein family. Interferon α 2A is one among the three variants of IFN-α2.[1] Recombinant human IFN-α-2a is expressed in human 293 cells as a glycosylated monomer of 165 amino acids, with an average molecular weight of 20 kDa (monomer).
Application
Interferon α 2A human has been used as an inhibitor of hepatitis D virus (HDV).[2]
Biochem/physiol Actions
Interferon Alpha 2A human is produced by many cell types in response to viral infection. IFN-α-2A has antiproliferative and antitumor activities, as well as induction of apoptosis and inflammatory response
Interferon α 2A might be implicated in the regression of proliferative diabetic retinopathy.[3] Telaprevir and pegylated interferon–α-2a (PEG-IFN–α-2a) serves as a potential therapeutic method for hepatitis C virus (HCV).[1] IFN α 2A along with IFN α 2b and IFN α2c exhibits anti-proliferative effect.[4]
Interferon α 2A might be implicated in the regression of proliferative diabetic retinopathy.[3] Telaprevir and pegylated interferon–α-2a (PEG-IFN–α-2a) serves as a potential therapeutic method for hepatitis C virus (HCV).[1] IFN α 2A along with IFN α 2b and IFN α2c exhibits anti-proliferative effect.[4]
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Interferon alpha-2a for proliferative diabetic retinopathy after complete laser panretinal photocoagulation treatment.
Leibovitch I, et al.
Ophthalmic Surgery, Lasers & Imaging Retina, 35(1), 16-22 (2004)
Guillaume Beauclair et al.
Journal of virology, 94(22) (2020-09-04)
Yellow fever virus (YFV) is an RNA virus primarily targeting the liver. Severe YF cases are responsible for hemorrhagic fever, plausibly precipitated by excessive proinflammatory cytokine response. Pathogen recognition receptors (PRRs), such as the cytoplasmic retinoic acid inducible gene I
Telaprevir and pegylated interferon?alpha?2a inhibit wild?type and resistant genotype 1 hepatitis C virus replication in patients
Kieffer T L, et al.
Hepatology, 46(3), 631-639 (2007)
Antitumor activities of interferon alpha, beta, and gamma and their combinations on human melanoma cells in vitro: changes of proliferation, melanin synthesis, and immunophenotype.
Garbe C, et al.
The Journal of Investigative Dermatology, 95(6), 231S-237S (1990)
Antitumor activities of interferon alpha, beta, and gamma and their combinations on human melanoma cells in vitro: changes of proliferation, melanin synthesis, and immunophenotype
Garbe C, et al.
The Journal of Investigative Dermatology, 95-95 (1990)
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
