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SML2679

Sigma-Aldrich

PFF-1

≥97% (HPLC)

Synonym(s):

3′,6′-Bis(diethylamino)-2-[(E)-(2-pyridinylmethylene)amino]-spiro[1H-isoindole-1,9′-[9H]xanthen]-3(2H)-one

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About This Item

Empirical Formula (Hill Notation):
C34H35N5O2
CAS Number:
Molecular Weight:
545.67
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥97% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

PFF-1 is a robust, cell penetrant and long time-laps (>30 min) fluorophore suitable for single-molecule localization microscopy experiments (SMLM). PFF-1 exhibits minimal phototoxicity and no apparent photobleaching. It was used to visualize movement of vesicles within cultured neurons.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Toward a highly sensitive and selective indole-rhodamine-based light-up probe for Hg2+ and its application in living cells
Yao T, Guo-Fang J
Tetrahedron Letters, 58, 2846-2849 null
Elias A Halabi et al.
Nature communications, 10(1), 1232-1232 (2019-03-16)
Photoswitchable molecules have multiple applications in the physical and life sciences because their properties can be modulated with light. Fluxional molecules, which undergo rapid degenerate rearrangements in the electronic ground state, also exhibit switching behavior. The stochastic nature of fluxional

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