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SML2596

Sigma-Aldrich

Sphynolactone-7

≥98% (HPLC)

Synonym(s):

4-Methyl-5-oxo-2,5-dihydrofuran-2-yl 4-(4-butoxyphenylsulfonyl)piperazine-1-carboxylate, SPL-7, SPL7

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About This Item

Empirical Formula (Hill Notation):
C20H26N2O7S
CAS Number:
2305752-57-0
Molecular Weight:
438.49
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CCCCOC1=CC=C(S(N2CCN(C(OC3C=C(C)C(O3)=O)=O)CC2)(=O)=O)C=C1

Biochem/physiol Actions

Sphynolactone-7 (SPL-7) is an active site-targeting, highly potent and selective strigolactone receptor ShHTL7 agonist (YLG competitive binding IC50 = 310 nM/ShHTL7, 1.2 μM/ShHTL8, >7.0 μM/ShHTL2-6, ShHTL9-11, AtD14) that acts as a seeds germination stimulant with femtomolar- and picomolar-level potency, respectively, toward the parasitic plants Striga hermonthica ecotypes and Orobanche minor, while exhibiting no Arabidopsis-stimulatory efficacy.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Daisuke Uraguchi et al.
Science (New York, N.Y.), 362(6420), 1301-1305 (2018-12-14)
The parasitic plant Striga hermonthica has been causing devastating damage to the crop production in Africa. Because Striga requires host-generated strigolactones to germinate, the identification of selective and potent strigolactone agonists could help control these noxious weeds. We developed a

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