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R115

Sigma-Aldrich

Reactive Blue 2

Synonym(s):

1-Amino-4-[[4-[[4-chloro-6-[[3 (or 4)-sulfophenyl]amino]-1,3,5-triazin-2-yl]amino]-3-sulfophenyl]amino]-9,10-dihydro-9,10-dioxo-2-anthracenesulfonic acid, Basilen Blue E-3G, Cibacron Blue F3G-A, Cibacron Blue F3GA, GST Inhibitor-1, Procion® Blue H-B

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About This Item

Empirical Formula (Hill Notation):
C29H17ClN7Na3O11S3
CAS Number:
12236-82-7
Molecular Weight:
840.10
Colour Index Number:
61211
Beilstein:
6561550
EC Number:
249-524-3
UNSPSC Code:
12171500
PubChem Substance ID:
24278686

color

dark blue

solubility

H2O: soluble

SMILES string

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4ccc(cc4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c5C(=O)c6ccccc6C(=O)c15)S([O-])(=O)=O.Nc7c(cc(Nc8ccc(Nc9nc(Cl)nc(Nc%10cccc(c%10)S([O-])(=O)=O)n9)c(c8)S([O-])(=O)=O)c%11C(=O)c%12ccccc%12C(=O)c7%11)S([O-])(=O)=O

Gene Information

human ... LPAR4(2846) , LTB4R(1241) , P2RY1(5028) , P2RY10(27334) , P2RY11(5032) , P2RY12(64805) , P2RY13(53829) , P2RY14(9934) , P2RY2(5029) , P2RY4(5030) , P2RY5(10161) , P2RY6(5031) , P2RY8(286530)

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Biochem/physiol Actions

P2Y purinoceptor antagonist; most potent antagonist for ATP-activated channels.

Legal Information

Procion is a registered trademark of Dystar Textilfarben GmbH & Co.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
120K1470
092K1176
053K3754
053K37541
072K1704

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T A Anikina et al.
Bulletin of experimental biology and medicine, 152(6), 672-674 (2012-07-18)
We studied the effect of uridine 5'-triphosphate in concentrations of 10(-10)-10(-6) M on myocardial contractile activity in 7-100-day-old rats. Analysis of isometric contraction of myocardial strips showed that uridine 5'-triphosphate reduced the strength of myocardial contraction in rats of all
Mehmet Odabası
Preparative biochemistry & biotechnology, 41(3), 287-304 (2011-06-11)
Cibacron Blue F3GA was covalently attached onto magnetic poly(vinyl alcohol) (mPVAL) beads (100-150 μm in diameter) for human serum albumin (HSA) adsorption from human plasma. Despite low nonspecific adsorption of HSA on mPVAL beads, Cibacron Blue F3GA attachment significantly increased
K Inoue et al.
British journal of pharmacology, 102(4), 851-854 (1991-04-01)
1. The effects of reactive blue 2 and brilliant blue G, which have been shown to block extracellular ATP-evoked responses, were investigated to discover whether these compounds act as P2-purinoceptor antagonists in PC12 phaeochromocytoma cells. 2. Reactive blue 2 (10
Angel Luis García-Villalón et al.
European journal of pharmacology, 660(2-3), 394-401 (2011-04-26)
Diadenosine tetraphosphate (AP4A) is a vasoactive mediator that may be released from platelet granules and that may reach higher plasma concentrations during coronary ischemia-reperfusion. The objective of this study was to analyze its coronary effects in such conditions. To this
Miao Li et al.
Protein and peptide letters, 20(4), 459-466 (2012-09-29)
From the fresh fruiting bodies of the mushroom Pleurotus eryngii a phytase with a molecular mass of 14 kDa was isolated. The isolation protocol entailed ion exchange chromatography on DEAE-cellulose and CM-cellulose, affinity chromatography on Affi-gel blue gel, and ion
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