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PZ0269

Sigma-Aldrich

PF-03049423

≥98% (HPLC)

Synonym(s):

3-[4-(2-Hydroxyethyl)-1-piperazinyl]-7-(6-methoxy-3-pyridinyl)-1-(2-propoxyethyl)-pyrido[3,4-b]pyrazin-2(1H)-one hydrochloride, 3-[4-(2-Hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one hydrochloride, PF-5

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About This Item

Empirical Formula (Hill Notation):
C24H32N6O4 · xHCl
CAS Number:
402955-58-2
Molecular Weight:
468.55 (free base basis)
UNSPSC Code:
41106305
PubChem Substance ID:
329823803
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 20 mg/mL, clear

storage temp.

room temp

SMILES string

CCCOCCN1C2=C(C=NC(C3=CN=C(OC)C=C3)=C2)N=C(N4CCN(CCO)CC4)C1=O.C

InChI

1S/C24H32N6O4.CH4/c1-3-13-34-14-11-30-21-15-19(18-4-5-22(33-2)26-16-18)25-17-20(21)27-23(24(30)32)29-8-6-28(7-9-29)10-12-31;/h4-5,15-17,31H,3,6-14H2,1-2H3;1H4

InChI key

BXMDZHBYGYPATN-UHFFFAOYSA-N

Biochem/physiol Actions

PF-03049423 is an orally active, brain penetrant phosphodiesterase 5 (PDE5) inihbitor.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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