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N9039

Sigma-Aldrich

nanoHA7

low endotoxin

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About This Item

UNSPSC Code:
12352201

form

film

quality

low endotoxin

impurities

≤1 EU/mg endotoxin

storage temp.

−20°C

General description

The nanoHA products are small-molecular weight hyaluronic acid oligomers prepared by chemoenzymatic synthesis using immobilized enzymes. The name of each nanoHA indicates the number of monosaccharide units in the oligomer. The reducing end contains N-acetyl-D-glucosamine.

Application

NanoHA has been used in a study to assess the nanomechanical properties of electrospun composite scaffolds. It has also been used in a study to investigate the influence of crystallite size of nanophased hydroxyapatite on fibronectin and osteonectin adsorption and on osteoblast adhesion and morphology.

Other Notes

nanoHA7 is a heptasaccharide containing three hyaluronan disaccharide subunits (GlcNAcβ4GlcAβ3GlcNAcβ4GlcAβ3GlcNAcβ4GlcAβ3GlcNAcβ4).
To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Physical form

Supplied lyophilized as the ammonium and/or sodium salt.

Analysis Note

Sold on the basis of carbohydrate as determined by carbazole assay.

Legal Information

nanoHA is a trademark of Hyalose LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Parul Tyagi et al.
Journal of nanoscience and nanotechnology, 9(8), 4839-4845 (2009-11-26)
Fibrous nanocomposite scaffolds were electrospun from dispersions of hydroxyapatite nanoparticles (nanoHA) in polycaprolactone (PCL) with varying nanoHA contents (from 0% to 50% by weight). Such scaffolds were produced to mimic the nano-features of the extracellular matrix (ECM) for natural bone
N Ribeiro et al.
Journal of colloid and interface science, 351(2), 398-406 (2010-09-03)
The characteristic topographical features (crystallite dimensions, surface morphology and roughness) of bioceramics may influence the adsorption of proteins relevant to bone regeneration. This work aims at analyzing the influence of two distinct nanophased hydroxyapatite (HA) ceramics, HA725 and HA1000 on
Staphylococcus aureus and Staphylococcus epidermidis adhesion to nanohydroxyapatite in the presence of model proteins
Ribeiro, M., et al.
Bio-medical materials and engineering, 7, 045010-045010 (2012)

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