This product is a neat or pure liquid. The compound is not available in solid form. The material is soluble in chloroform at 0.1 mg/mL.
M7891
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
BioReagent, for silylations, LiChropur™
Synonym(s):
N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA
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About This Item
Linear Formula:
CF3CON(CH3)Si(CH3)3
CAS Number:
Molecular Weight:
199.25
Beilstein:
1941550
EC Number:
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:
NACRES:
NA.25
Pricing and availability is not currently available.
Recommended Products
vapor density
>1 (vs air)
Quality Level
vapor pressure
8.8 mmHg ( 27 °C)
product line
BioReagent
form
liquid
quality
for silylations, LiChropur™
reaction suitability
reaction type: Silylations
reagent type: derivatization reagent
technique(s)
gas chromatography (GC): suitable
refractive index
n20/D 1.38 (lit.)
bp
130-132 °C (lit.)
solubility
chloroform: soluble 0.1 mg/mL
density
1.07 g/mL at 25 °C (lit.)
1.075 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
CN(C(=O)C(F)(F)F)[Si](C)(C)C
InChI
1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
InChI key
MSPCIZMDDUQPGJ-UHFFFAOYSA-N
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General description
N-Methyl-N-(trimethylsilyl)trifluoroacetamide(MSTFA) is a BioReagent commonly used for silylation reactions in analyticalchemistry.[1]
Application
N-Methyl-N-(trimethylsilyl)trifluoroacetamide can be used:
- In the derivatization step of the metabolomics analysis using gas chromatography/mass spectrometry (GC/MS).[2]
- Derivatization reagent in gas chromatography with flame ionization detection (GC-FID) analysis.
Packaging
Sealed ampules contain 1 ml. Gram sizes are in screw-cap bottles.
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
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Description
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
77.0 °F - closed cup
Flash Point(C)
25 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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GC-MS analysis of silylated metabolites is a sensitive method that covers important metabolite groups such as sugars, amino acids and non-amino organic acids, and it has become one of the most important analytical methods for exploring the metabolome. Absolute quantitative
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Journal of chromatography. A, 1131(1-2), 192-202 (2006-08-08)
A novel method has been developed to simultaneously determine and quantify seven organic UV filters employing liquid (solid)-liquid extraction, derivatization with N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) and gas chromatography with mass spectrometric detection in various environmental matrices. The UV filters determined were:
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Journal of chromatography. A, 1217(11), 1748-1760 (2010-02-13)
An alternative method for the sensitive determination of several drugs of abuse and some of their metabolites in surface and sewage water samples is proposed. Analytes are concentrated using a solid-phase extraction (SPE) sorbent, converted into the corresponding trimethylsilyl derivatives
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If I order this reagent in solid form, then how am I supposed to reconstitute it? I mean, with which reagent and to what concentration?
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