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L8250

Sigma-Aldrich

DL-Leucinamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H14N2O · HCl
CAS Number:
Molecular Weight:
166.65
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Assay

≥98% (TLC)

form

powder

color

white

SMILES string

Cl.CC(C)CC(N)C(N)=O

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H

InChI key

VSPSRRBIXFUMOU-UHFFFAOYSA-N

Biochem/physiol Actions

DL-Leucinamide hydrochloride is a racemic mixture of D- and L- enantiomers of leucinamide. Leucinamide is an amide derivative of leucine found at the C-terminal of various peptides such as the PAR-2 activating peptide SLIGRL-NH(2).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Yasuhiko Hashida et al.
Journal of biochemistry, 141(6), 879-888 (2007-04-05)
Thermolysin activity in the hydrolysis of N-[3-(2-furyl)acryloyl]-glycyl-l-leucine amide (FAGLA) and FA-l-leucyl-l-alanine amide (FALAA) was examined at various Co(2+) and Ca(2+) concentrations. It decreased to 28% with increasing [Co(2+)] up to 18 mM. The Co(2+)-dependent inactivation was in part suppressed by
Hidenobu Komeda et al.
Applied microbiology and biotechnology, 70(4), 412-421 (2005-07-08)
Brevundimonas diminuta TPU 5720 produces an amidase acting L-stereoselectively on phenylalaninamide. The enzyme (LaaA(Bd)) was purified to electrophoretic homogeneity by ammonium sulfate fractionation and four steps of column chromatography. The final preparation gave a single band on SDS-PAGE with a
R Pacheco et al.
Analytical biochemistry, 346(1), 49-58 (2005-09-28)
This study demonstrates the use of Fourier transform infrared (FTIR) spectroscopy for monitoring both synthesis and hydrolysis reactions catalyzed by a recombinant amidase (EC 3.5.1.4) from Pseudomonas aeruginosa. The kinetics of hydrolysis of acetamide, propionamide, butyramide, acrylamide, benzamide, phenylalaninamide, alaninamide
Andrew R Conrad et al.
The journal of physical chemistry. A, 115(34), 9676-9681 (2011-05-12)
Rotational spectra were recorded for two isotopic species of two conformers of the amide derivative of leucine in the range of 10.5-21 GHz and fit to a rigid rotor Hamiltonian. Ab initio calculations at the MP2/6-311++G(d,p) level identified the low
[Leucinamide specific cytosol leucine aminopeptidase].
T Kanno
Rinsho byori. The Japanese journal of clinical pathology, 30(5), 502-506 (1982-05-01)

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