F5180

Anti-Fibroblast Growth Factor-Basic antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-BFGF, Anti-FGF2, Anti-FGFB, Anti-HBGF-2
• MDL number: MFCD00212948
• UNSPSC Code: 51111800
• NACRES: NA.41

Properties

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: bovine, human
• technique(s): immunohistochemistry: 5-15 μg/mL; neutralization: suitable; western blot: 0.1-0.2 μg/mL
• UniProt accession no.: P09038
• application(s): research pathology
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: bovine ... FGF2(281161) ; human ... FGF2(2247)

Description

Immunogen

purified bovine fibroblast growth factor basic peptide (146 aa).

Biochem/physiol Actions

Fibroblast Growth Factor Basic (also known as bFGF) is a pleotropic cytokine that that is a potent mitogenic factor. On binding to its cognate receptor tyrosine kinase, FGFR, bFGF is capable of activation of pathways such as MAPK and PI3K and produce cellular effects in varied cell types. Fibroblast Growth Factor-basic is reported to induce proliferation of fibroblasts, differentiation, wound healing and regeneration, limb formation, tissue remodeling and angiogenesis.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves