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D3664

Sigma-Aldrich

Deoxyribonucleic acid sodium salt from calf thymus

suitable for substrate for DNase (Readily soluble)

Synonym(s):

CT-DNA, calf thymus DNA, DNA sodium salt from calf thymus, Thymonucleic acid sodium salt

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About This Item

CAS Number:
73049-39-5
MDL number:
MFCD00130922
UNSPSC Code:
41106305
eCl@ss:
32160414
NACRES:
NA.51

form

powder or crystals

suitability

suitable for substrate for DNase (Readily soluble)

storage temp.

2-8°C

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Application

Calf thymus DNA (CT-DNA) is a natural DNA widely used in studies of DNA binding anticancer agents and DNA binding agents that modulate DNA structure and function. Calf thymus DNA is also used in physicochemical studies of DNA behavior in solution.

Packaging

Preweighed vials prepared from D1501

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Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kristin Grøsvik et al.
Frontiers in microbiology, 11, 263-263 (2020-03-12)
The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine (m3A), which in Escherichia coli is removed by m3A-DNA glycosylase I (Tag) and II
Abdollah Zakeri Siavashani et al.
Biomaterials science, 8(1), 148-162 (2019-10-31)
Implantation of temporary and permanent biomaterials in the body leads to a foreign body reaction (FBR), which may adversely affect tissue repair processes and functional integration of the biomaterial. However, modulation of the inflammatory response towards biomaterials can potentially enable
Xingyi Chen et al.
Molecular pharmaceutics, 16(6), 2690-2699 (2019-05-01)
The nucleotide-binding domain and leucine-rich repeat-containing family, pyrin domain-containing 3 (NLRP3) inflammasome is a key regulator of innate immune responses, and its aberrant activation is implicated in the pathogenesis of many diseases such as Alzheimer's disease and type 2 diabetes.
Coordination ability and biological activity of a naringenin thiosemicarbazone.
Katarzyna Brodowska et al.
Journal of inorganic biochemistry, 165, 36-48 (2016-10-21)
Claire L Camp et al.
Analytical and bioanalytical chemistry, 402(1), 367-372 (2011-08-31)
The determination of total deoxyribonucleic acid (DNA) concentration is of great importance in many biological and bio-medical analyses. The quantification of DNA is traditionally performed by UV spectroscopy; however the results can be affected greatly by the sample matrix. The
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Protocols

Enzymatic Assay of Deoxyribonuclease I (EC 3.1.21.1)

To standardize a procedure for the enzymatic assay of Deoxyribonuclease I.

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