A6220

N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin

≥97% (HPLC), powder

• Synonym(s): Ac-IEPD-AMC
• Empirical Formula (Hill Notation): C₃₂H₄₁N₅O₁₁
• Molecular Weight: 671.69
• MDL number: MFCD02259622
• UNSPSC Code: 12352209
• PubChem Substance ID: 329770886
• NACRES: NA.32

Properties

• Quality Level: 200
• Assay: ≥97% (HPLC)
• form: powder
• solubility: DMSO/DMF: 1 mg/mL
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2
• InChI: 1S/C32H41N5O11/c1-5-16(2)28(33-18(4)38)31(46)35-21(10-11-25(39)40)32(47)37-12-6-7-23(37)30(45)36-22(15-26(41)42)29(44)34-19-8-9-20-17(3)13-27(43)48-24(20)14-19/h8-9,13-14,16,21-23,28H,5-7,10-12,15H2,1-4H3,(H,33,38)(H,34,44)(H,35,46)(H,36,45)(H,39,40)(H,41,42)/t16-,21-,22-,23-,28-/m0/s1
• InChI key: XDMHHBKPMUGLEA-MNTOYCOOSA-N
• Gene Information: human ... CARD8(22900) , CASP8(841) , CASP8AP2(9994) , CFLAR(8837) , GZMB(3002) ; mouse ... CFLAR(117279) , GZMB(171528) ; rat ... CASP8(12370) , CFLAR(12633) , GZMB(14939) , RGD1561819(502004) , RGD1562700(502007)

Description

Amino Acid Sequence

NAc-Ile-Glu-Pro-Asp-AMC

Substrates

Fluorogenic substrate for caspase 8 and granzyme B.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves