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270482

Sigma-Aldrich

2-Methoxyethanol

suitable for HPLC, ≥99.9%

Synonym(s):

Ethylene glycol monomethyl ether, Methyl glycol

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About This Item

Linear Formula:
CH3OCH2CH2OH
CAS Number:
109-86-4
Molecular Weight:
76.09
Beilstein:
1731074
EC Number:
203-713-7
MDL number:
MFCD00002867
UNSPSC Code:
12190000
PubChem Substance ID:
329752943
NACRES:
NA.21

vapor density

2.62 (vs air)

vapor pressure

6.17 mmHg ( 20 °C)

Assay

≥99.9%

form

liquid

autoignition temp.

548 °F

purified by

glass distillation

expl. lim.

24.5 %

technique(s)

HPLC: suitable

impurities

<0.050% water

evapn. residue

<0.0005%

refractive index

n20/D 1.402 (lit.)

pH

5.0-7.0 (25 °C)

bp

124-125 °C (lit.)

mp

−85 °C (lit.)

density

0.965 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 213 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 260 nm Amax: 0.05
λ: 300-400 nm Amax: 0.01

application(s)

food and beverages

SMILES string

COCCO

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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General description

This solvent is glass distilled, submicron filtered and subjected to rigorous specification testing to provide lot-to-lot consistency.

Application

Designed for use with HPLC instrumentation and organic synthesis applications.
Used in the LC-MS of rat urine samples for determination of 2-methoxyethanol.

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B - STOT RE 2 - STOT SE 1

Target Organs

Immune system, thymus

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

104.0 °F - closed cup

Flash Point(C)

40 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Robert A Hartman et al.
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Conductometric, viscometric, and spectroscopic investigations on the solvation phenomena of alkali-metal ions and ion pairs in 2-methoxyethanol.
Das B and Hazra DK.
The Journal of Physical Chemistry, 99(1), 269-273 (1995)
Alberto Dessy et al.
Colloids and surfaces. B, Biointerfaces, 87(2), 236-242 (2011-06-17)
Therapeutic properties of Dead Sea Water (DSW) in the treatment of skin diseases such as atopic dermatitis, psoriasis and photo aging UV damaged skin have been well established. DSW is in fact rich in minerals such as calcium, magnesium, sodium
H-Y Chang et al.
Occupational and environmental medicine, 61(8), 697-702 (2004-07-20)
To evaluate the protective effectiveness of gloves from occupational exposure to 2-methoxyethanol (2-ME); and to examine the association of 2-methoxyacetic acid (MAA) in urine and plasma collected simultaneously from low 2-ME exposure and high 2-ME exposure workers in a semiconductor
Makoto Takei et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 643-652 (2010-07-10)
Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order
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