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12654

Sigma-Aldrich

Potassium nitrite

meets analytical specification of FCC, 97-100.5%

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About This Item

Empirical Formula (Hill Notation):
KNO2
CAS Number:
7758-09-0
Molecular Weight:
85.10
EC Number:
231-832-4
MDL number:
MFCD00011408
UNSPSC Code:
12352302
PubChem Substance ID:
329749790
NACRES:
NA.21

Assay

97-100.5%

form

crystals

quality

meets analytical specification of FCC

impurities

≤0.001% heavy metals (as Pb)

mp

350 °C (dec.) (lit.)

solubility

water: soluble 0.35 part
alcohol: slightly soluble

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

As: ≤1 mg/kg
Fe: ≤10 mg/kg
Pb: ≤4 mg/kg

SMILES string

[K+].[O-]N=O

InChI

1S/K.HNO2/c;2-1-3/h;(H,2,3)/q+1;/p-1

InChI key

BXNHTSHTPBPRFX-UHFFFAOYSA-M

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Application

Potassium nitrite has been used for determining the bacteriostatic and fungistatic activity of acidified nitrite. It has also been used as a supplement in buffer for investigating the impact of nitrite on nosocomial pathogens including C. difficile spores. Adulterants such as “Klear” and “Whizzies” contain potassium nitrite which masks tests for abused drugs in urine. Hence potassium nitrite is used along with Klear and Urine Luck for preparing adulterated urine for drug-of-abuse testing.

Biochem/physiol Actions

Potassium nitrite is a strong oxidizing agent that enhances seeds to germinate without a pre-incubation period and without ethylene.

Signal Word

Danger

Hazard Statements

H272,H301,H400

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Ox. Sol. 2

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Agam Rao et al.
Antimicrobial agents and chemotherapy, 50(11), 3901-3904 (2006-10-27)
Exposure to pH 1 or 2 buffers or acidic gastric contents resulted in the killing of vancomycin-resistant Enterococcus sp., Klebsiella pneumoniae, Staphylococcus aureus, and Candida glabrata but not Clostridium difficile spores. Nitrite enhanced killing under acidic conditions, but significant killing
Ethylene, Nitrate and Nitrite Interactions in the Promotion of Dark Germination of Common Purslane Seeds.
<BIG>G. H. Egley</BIG>
Annals of Botany, 53, 833-840 (1984)
R Weller et al.
Journal of applied microbiology, 90(4), 648-652 (2001-04-20)
Nitric oxide is generated from sweat nitrite in the acidic environment of the skin surface and is thought to contribute to protection against infection. This study examined the sensitivity of Trichophyton mentagrophytes, T. rubrum, Candida albicans, Streptococcus pyogenes, Staphylococcus aureus
D Billen
Radiation research, 111(2), 354-360 (1987-08-01)
When cells are exposed to ionizing radiation, they suffer lethal damage (LD), potentially lethal damage (PLD), and sublethal damage (SLD). All three forms of damage may be caused by direct or indirect radiation action or by the interaction of indirect
R Weller et al.
Journal of the American Academy of Dermatology, 38(4), 559-563 (1998-04-29)
Nitric oxide is continually released from normal skin and has antimicrobial effects. An acidified nitrite cream releases supraphysiologic concentrations of nitric oxide and is fungicidal in vitro. The purpose of this study was to assess the efficacy of an acidified
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