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T6654

Supelco

Ticlopidine hydrochloride

analytical standard, for drug analysis

Synonym(s):

5-(o-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

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About This Item

Empirical Formula (Hill Notation):
C14H14ClNS · HCl
CAS Number:
53885-35-1
Molecular Weight:
300.25
EC Number:
258-837-4
MDL number:
MFCD00079606
UNSPSC Code:
41116107
PubChem Substance ID:
329826850
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

100

Assay

≥99%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.Clc1ccccc1CN2CCc3sccc3C2

InChI

1S/C14H14ClNS.ClH/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14;/h1-4,6,8H,5,7,9-10H2;1H

InChI key

MTKNGOHFNXIVOS-UHFFFAOYSA-N

Gene Information

human ... P2RY12(64805)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Ticlopidine hydrochloride has been used as an analytical standard to investigate the developmental toxicity and teratogenic potential of ticlopidine in Xenopus laevis embryos and human endothelial cells using a frog embryo teratogenesis assay-Xenopus (FETAX) and blood and lymph vessel formation assay.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK6162
BCCF8044
BCCF4027
BCCC6457
BCBZ4684

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Characterization of ticlopidine-induced developmental and teratogenic defects in Xenopus embryos and human endothelial cells.
Park SM, et al.
Chemico-Biological Interactions, 240, 172-178 (2015)
Jan H Cornel et al.
American heart journal, 168(1), 76-87 (2014-06-24)
To further explore the impact of smoking on antiplatelet activity and treatment response, we evaluated time-dependent relationships between smoking status with on-treatment platelet reactivity and clinical outcomes for prasugrel vs. clopidogrel in patients with acute coronary syndromes managed medically without
Thomas O Bergmeijer et al.
American heart journal, 168(1), 16-22 (2014-06-24)
In patients with ST-segment elevation myocardial infarction (STEMI) who undergo primary percutaneous coronary intervention (pPCI), the use of dual antiplatelet therapy is essential to prevent atherothrombotic complications. Therefore, patients are treated with acetylsalicylic acid and clopidogrel, prasugrel, or ticagrelor. Clopidogrel
Peter Damman et al.
The American journal of cardiology, 113(1), 64-69 (2013-10-31)
Large real-world registry data are important for understanding the current use and outcomes of novel therapies. The aim of this study was to assess treatment patterns and outcomes in patients who underwent percutaneous coronary intervention (PCI) with prasugrel or clopidogrel.
Colin P Derdeyn et al.
Lancet (London, England), 383(9914), 333-341 (2013-10-31)
Early results of the Stenting and Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis trial showed that, by 30 days, 33 (14·7%) of 224 patients in the stenting group and 13 (5·8%) of 227 patients in the medical
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