The product expiration date is listed on the label and the lot specific Certificate of Analysis. This product is assigned a shelf life of approximately 3 years from the quality release date. Please see the link below to review a sample Certificate:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/S6387-25G0000252608.pdf
S6387
Sulfadiazine sodium salt
≥98% (HPLC)
Synonym(s):
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide sodium salt, SPS Agar Supplement
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About This Item
Empirical Formula (Hill Notation):
C10H9N4NaO2S
CAS Number:
Molecular Weight:
272.26
Beilstein:
4068213
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.
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grade
analytical standard
Quality Level
Assay
≥98% (HPLC)
form
crystalline powder
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
SMILES string
Nc1ccc(cc1)S(=O)(=O)N([Na])c2ncccn2
InChI
1S/C10H9N4O2S.Na/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
InChI key
JLDCNMJPBBKAHH-UHFFFAOYSA-N
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General description
Sulfadiazine sodium salt is a broad-spectrum antibiotic belonging to the class of sulfonamides[1] commonly used against gram-postive and gram-negative microorganisms in humans and veterinary medication. Its mode of action involves inhibiting the multiplication of bacteria as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle.[2]
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfadiazine may be used as an internal standard for the determination of sulfapyridine in biological samples using high-performance liquid chromatography technique.[3]
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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High-performance liquid chromatographic method for determination of sulfapyridine in human saliva using post-column, in-line derivatization with fluorescamine
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Journal of Chromatography. B, Biomedical Applications, 273(2), 103-106 (1983)
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In this study, we analyzed the global metabolomic changes associated with Toxoplasma gondii infection in mice in the presence or absence of sulfadiazine sodium (SDZ) treatment. BALB/c mice were infected with T. gondii GT1 strain and treated orally with SDZ
Vanessa Estato et al.
The American journal of pathology, 188(11), 2674-2687 (2018-08-20)
Toxoplasmosis is one of the leading parasitic diseases worldwide. Some data suggest that chronic acquired toxoplasmosis could be linked to behavioral alterations in humans. The parasite infects neurons, forming immunologically silent cysts. Cerebral microcirculation homeostasis is determinant to brain functions
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