Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

84480

Sigma-Aldrich

Sanguinarine chloride

≥98.0% (HPLC)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C20H14ClNO4
CAS Number:
5578-73-4
Molecular Weight:
367.78
Beilstein:
3832138
MDL number:
MFCD00012126
UNSPSC Code:
12352203
Pricing and availability is not currently available.

Assay

≥98.0% (HPLC)

solubility

methanol: 20 mg/mL, clear, orange

SMILES string

[Cl-].C[n+]1cc2c3OCOc3ccc2c4ccc5cc6OCOc6cc5c14

InChI

1S/C20H14NO4.ClH/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21;/h2-8H,9-10H2,1H3;1H/q+1;/p-1

InChI key

GIZKAXHWLRYMLE-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

replaced by

Product No.
Description
Pricing

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Xiaofeng Niu et al.
Toxicology and applied pharmacology, 267(3), 256-265 (2013-01-29)
The quaternary ammonium salt, sanguinarine (SANG), is of great practical and research interest because of its pronounced, widespread physiological effects, which promote anti-microbial and anti-inflammatory responses in experimental animals. Although SANG is originally shown to possess anti-inflammatory properties and it
Irene Bessi et al.
ACS chemical biology, 7(6), 1109-1119 (2012-04-11)
G-quadruplex structures can be formed at the single-stranded overhang of telomeric DNA, and ligands able to stabilize this structure have recently been identified as potential anticancer drugs. Among the potential G-quadruplex binders, we have studied the binding ability of berberine
Fei Wu et al.
PloS one, 7(11), e48251-e48251 (2012-11-28)
Small molecules that can specifically bind to a DNA abasic site (AP site) have received much attention due to their importance in DNA lesion identification, drug discovery, and sensor design. Herein, the AP site binding behavior of sanguinarine (SG), a
Haowei Li et al.
Biochemical and biophysical research communications, 430(3), 951-956 (2012-12-25)
Sanguinarine is a natural plant extract that has been supplemented in a number of gingival health products to suppress the growth of dental plaque. However, whether sanguinarine has any effect on teeth and alveolar bone health is still unclear. In
Naveen Bojjireddy et al.
Archives of biochemistry and biophysics, 537(2), 192-197 (2013-08-01)
The effects of sanguinarine on IgE mediated early signaling mechanisms leading to inflammatory mediators release were investigated. Pretreatment of RBL 2H3 cells with sanguinarine inhibited IgE induced activation of type II PtdIns 4-kinase activity. Concomitant with type II PtdIns 4-kinase
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service