33871
2-Nitrobenzaldehyde semicarbazone
VETRANAL®, analytical standard
Synonym(s):
2-NP-SCA, 4-(2-Nitrobenzylidene)semicarbazide
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About This Item
Empirical Formula (Hill Notation):
C8H8N4O3
CAS Number:
Molecular Weight:
208.17
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
SMILES string
NC(=O)N\N=C\c1ccccc1[N+]([O-])=O
InChI
1S/C8H8N4O3/c9-8(13)11-10-5-6-3-1-2-4-7(6)12(14)15/h1-5H,(H3,9,11,13)/b10-5+
InChI key
OEOKLBSECDAYSM-BJMVGYQFSA-N
General description
2-Nitrobenzaldehyde semicarbazone is a semicarbazone derivative of 2-Nitrobenzaldehyde.
Application
2-Nitrobenzaldehyde semicarbazone (2-NBA-SC) may be used as an analytical reference standard for the determination of 2-NBA-SC in:
- Animal muscle tissues by solid-phase extraction (SPE) and high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) equipped with electrospray ionization (ESI) source and multiple reaction monitoring (MRM) detection.
- Milk of dairy cows by LC-MS/MS with selected reaction monitoring (SRM) detection.
- Azodicarbonamide-treated flour samples by isotope dilution liquid chromatography coupled to ESI-LC-MS/MS.
- Shrimp dosed with nitrofurans by ESI-LC-MS/MS with SRM detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Derivatized standard for the assay of nitrofurans in animal tissue by LC/MS
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Liquid chromatography- tandem mass spectrometry for the determination of protein-bound residues in shrimp dosed with nitrofurans.
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Journal of Agricultural and Food Chemistry, 53(23), 8934-8939 (2005)
Microwave-assisted Synthesis and Bioevaluation of Some Semicarbazones.
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Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography-tandem mass spectrometry.
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Determination of nitrofuran residues in milk of dairy cows using liquid chromatography- tandem mass spectrometry.
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Journal of Agricultural and Food Chemistry, 55(6), 2129-2135 (2007)
Adam Becalski et al.
Journal of agricultural and food chemistry, 52(18), 5730-5734 (2004-09-18)
Semicarbazide was previously found in foods that were in contact with rubber gaskets foamed at high temperatures with a blowing agent azodicarbonamide. Because azodicarbonamide is an approved flour additive in certain countries, we set out to ascertain if semicarbazide is
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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