165300

L-(+)-2-Amino-4-phosphonobutyric Acid

• Synonym(s): L-(+)-2-Amino-4-phosphonobutyric Acid, L-AP4
• Empirical Formula (Hill Notation): C₄H₁₀NO₅P
• CAS Number: 23052-81-5
• Molecular Weight: 183.10
• MDL number: MFCD00083244
• UNSPSC Code: 12352200

Properties

• Assay: ≥98% (HPLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: dilute aqueous base: 5 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/p-2/t3-/m0/s1
• InChI key: DDOQBQRIEWHWBT-VKHMYHEASA-L

Description

General description

Phosphonic acid analog of L-glutamic acid. A selective group III metabotropic glutamate receptor agonist. Also a potent, pathway-specific synaptic depressant.

Warning

Toxicity: Irritant (B)

Other Notes

Pin, J.-P., and Duvoisin, R. 1995. Neuropharmacology 34, 1.
Saugstad, J.A., et al. 1995. Mol. Pharmacol. 45, 367.
Tones, M.A., et al. 1995. NeuroReport 7, 117.
Schoepp, D.D. 1994. Neurochem. Int. 24, 439.
Nakanishi, S. 1992. Science 258, 597.
Tanabe, Y., et al. 1992. Neuron 8, 169.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable