Skip to Content
Merck
All Photos(1)

Documents

A7302

Sigma-Aldrich

4-Acetamidophenol

98%

Synonym(s):

Acetaminophen, 4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CONHC6H4OH
CAS Number:
103-90-2
Molecular Weight:
151.16
Beilstein:
2208089
EC Number:
203-157-5
MDL number:
MFCD00002328
UNSPSC Code:
12352100
PubChem Substance ID:
24891200

Assay

98%

form

crystals

mp

168-172 °C (lit.)

storage temp.

room temp

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

Gene Information

human ... FAAH(2166) , PTGS1(5742) , PTGS2(5743) , TRPV1(7442)

Looking for similar products? Visit Product Comparison Guide

Application

4-Acetamidophenol may be used to synthesize cis-and trans-4-acetamidocyclohexanol in the presence of Mg, Na or Ce modified ruthenium-supported catalysts.
Analgesic.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

364.3 °F - Pensky-Martens closed cup

Flash Point(C)

184.6 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chemically modified polymeric filtration membranes for the selective elimination of active pharmaceutical ingredients from water.
Gong YS, et al.
Polymers For Advanced Technologies, 24(10), 861-865 (2013)
Partial molar volume of paracetamol in water, 0.1 M HCl and 0.154 M NaCl at T= (298.15, 303.15, 308.15 and 310.65) K and at 101.325 kPa.
Iqbal MJ and Malik QM.
The Journal of Chemical Thermodynamics, 37(12), 1347-1350 (2005)
S Ahmed et al.
Biodegradation, 12(5), 303-309 (2002-05-09)
Though many microorganisms that are capable of using phenol as sole source of carbon have been isolated and characterized, only a few organisms degrading substituted phenols have been described to date. In this study, one strain of microorganism that is
Influence of modifiers on the performance of Ru-supported catalysts on the stereoselective hydrogenation of 4-acetamidophenol.
Bachiller-Baeza B, et al.
Applied Surface Science, 253(10), 4805-4813 (2007)
Mitchell R McGill et al.
Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service