47296
o-Fluoro-L-phenylalanine
puriss., ≥99.0% (sum of enantiomers, HPLC)
Synonym(s):
2-Fluoro-L-phenylalanine
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About This Item
Empirical Formula (Hill Notation):
C9H10FNO2
CAS Number:
Molecular Weight:
183.18
Beilstein:
2805791
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
grade
puriss.
Assay
≥99.0% (sum of enantiomers, HPLC)
optical activity
[α]20/D −14±1°, c = 1% in H2O
optical purity
enantiomeric ratio: ≥99.5:0.5 (TLC)
SMILES string
N[C@@H](Cc1ccccc1F)C(O)=O
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Kensuke Okuda et al.
Biochemistry, 44(17), 6675-6684 (2005-04-27)
The ribosome-catalyzed peptidyl transferase reaction displays a complex pH profile resulting from two functional groups whose deprotonation is important for the reaction, one within the A-site substrate and a second unidentified group thought to reside in the rRNA peptidyl transferase
T T Otani et al.
Journal of pharmaceutical sciences, 71(2), 214-216 (1982-02-01)
Twelve derivatives of 0-fluoro-dl-phenylalanine containing fluorine, chlorine, methoxy, and nitro radicals in various positions of the aromatic ring of the benzoyl group were prepared and tested in a Lactobacillus casei system. It was found that most substitutions in the benzoyl
J Hatazawa et al.
Annals of nuclear medicine, 8(3), 213-217 (1994-08-01)
We studied the brain uptake of amino acid in a patient with acute cerebral infarction with L-[2-(F-18)]fluorophenylalanine and positron emission tomography. The increased accumulation of the ligand was specifically found in the peri-infarct area where oxygen metabolism was still maintained
H Ito et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 36(7), 1232-1237 (1995-07-01)
Neutral amino acids (NAAs) are transported from the blood to the brain using the same carrier system in a competitive fashion. The purpose of this study is to establish a method for evaluating neutral amino acid transport at the blood-brain
Elfriede Pittler et al.
Electrophoresis, 30(16), 2897-2904 (2009-08-06)
This work deals with the application of silica-based ligand-exchange chiral stationary phases (CSPs) for the enantioseparation of underivatized amino acids, alpha-hydroxy acids, and dipeptides with packed CEC. Two different possibilities of preparing silica-based CSPs are presented. One phase contains L-4-hydroxyproline
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