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386588

Sigma-Aldrich

Pinacolyl methylphosphonate

97%

Synonym(s):

1,2,2-Trimethylpropyl methylphosphonate, 3,3-Dimethylbutan-2-yloxy(methyl)phosphinic acid, Mono(1,2,2-trimethylpropyl) methylphosphonate, O-Pinacolyl hydrogen methylphosphonate, O-Pinacolyl methylphosphonate, PMPA, Pinacolyl hydrogen methylphosphonate, [(3,3-Dimethylbutan-2-yl)oxy](methyl)phosphinic acid

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About This Item

Linear Formula:
CH3P(O)(OH)OCH(CH3)C(CH3)3
CAS Number:
616-52-4
Molecular Weight:
180.18
MDL number:
MFCD00192402
UNSPSC Code:
12352100
PubChem Substance ID:
24864102
NACRES:
NA.22
form:
liquid
Assay:
97%
Pricing and availability is not currently available.

Quality Level

100

Assay

97%

form

liquid

refractive index

n20/D 1.434 (lit.)

bp

96-106 °C/8 mmHg (lit.)

density

1.032 g/mL at 25 °C (lit.)

SMILES string

CC(OP(C)(O)=O)C(C)(C)C

InChI

1S/C7H17O3P/c1-6(7(2,3)4)10-11(5,8)9/h6H,1-5H3,(H,8,9)

InChI key

BLALDUPQYCGKAG-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315

Hazard Classifications

Acute Tox. 4 Oral - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

165.2 °F - closed cup

Flash Point(C)

74 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
0000340975
0000340975
0000215740
0000252065
MKCP9349

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Dimethyl methylphosphonate ≥98%

Sigma-Aldrich

D169102

Dimethyl methylphosphonate

Manisha Sathe et al.
The Analyst, 137(2), 406-413 (2011-11-19)
Immunoassay detection of O-pinacolyl methylphosphonic acid (PMPA) employing direct coating of N-2-aminoethyl-O-pinacolyl methylphosphonate (hapten B) on microtiter plates is reported. Coating was achieved by covalently linking hapten B to a glutaraldehyde (GA) polymer network directly bound to the polystyrene (PS)
B Rosenwirth et al.
Journal of medical primatology, 28(4-5), 195-205 (1999-12-11)
Combination chemotherapy using potent anti-retroviral agents has led to significant advances in the clinical management of human immunodeficiency virus (HIV) disease. However, the emergence of multiple drug-resistant mutants, the high need for compliance to adhere to demanding drug-dosing schemes, and
Harri Koskela et al.
Analytical chemistry, 90(14), 8495-8500 (2018-06-12)
The NMR-observable nuclei of the acidic and basic compounds experience pH dependence in chemical shift. This phenomenon can be exploited in NMR titrations to determine p Ka values of compounds, or in pH measurement of solutions using dedicated pH reference
Sung-Up Choi et al.
Journal of pharmaceutical sciences, 97(2), 931-943 (2007-06-05)
We have investigated the ability of lipid-indinavir particles composed of 3-to-1 lipid-drug molar ratio to encapsulate an aqueous marker calcein and anti-HIV drug (3)H-phosphonylmethoxypropyl-adenine (PMPA). Even at a high density of indinavir associated to lipid-indinavir nanoparticles, they form an enclosed
Looking down the drug pipeline.
J Cadman
GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 12(3), 5-9 (2001-05-22)
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