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857319

Sigma-Aldrich

Chloramine-T hydrate

95%

Synonym(s):

N-Chloro-p-toluenesulfonamide sodium salt hydrate

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About This Item

Linear Formula:
CH3C6H4SO2N(Cl)Na · xH2O
CAS Number:
Molecular Weight:
227.64 (anhydrous basis)
EC Number:
MDL number:
UNSPSC Code:
12352002
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

Assay

95%

form

solid

reaction suitability

reagent type: oxidant

mp

167-170 °C (dec.) (lit.)

SMILES string

O.Cc1ccc(cc1)S(=O)(=O)N([Na])Cl

InChI

1S/C7H7ClNO2S.Na.H2O/c1-6-2-4-7(5-3-6)12(10,11)9-8;;/h2-5H,1H3;;1H2/q-1;+1;

InChI key

BXSDMMPOQRECKB-UHFFFAOYSA-N

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Application

A review.[1]
Capable of oxidative cyclization to produce various heterocycles.[2][3]
Nitrene source for aziridinations[4][5][6][7][8][9] and aminohydroxylations.[10][11][12]
Reactant for:
  • Preparation of factor Xa inhibitors as novel anticoagulants

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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J. Sci. Ind. Res., 49, 13-13 (1990)
Ines Sherifi et al.
Scientific reports, 10(1), 14030-14030 (2020-08-21)
Tissue-engineered grafts may be useful in Anterior Cruciate Ligament (ACL) repair and provide a novel, alternative treatment to clinical complications of rupture, harvest site morbidity and biocompatibility associated with autografts, allografts and synthetic grafts. We successfully used supercritical carbon dioxide
Rudolph, J. et al
Angewandte Chemie (International Edition in English), 35, 2810-2810 (1996)
Mogilaiah, K.; Reddy, G. R.
J. Chem. Res. (M), 145-145 (2004)
Jong Deok Na et al.
Food & function, 10(2), 1225-1234 (2019-02-13)
Betaine is a methyl donor utilized in regeneration of methionine from homocysteine in a metabolic reaction catalyzed by betaine-homocysteine methyltransferase (BHMT), an enzyme mostly localized in the liver. However, we recently showed that the metabolism of sulfur-containing amino acids in

Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. What is your test method for Chloramine-T hydrate. Can you please give detailed information with reference, if applicable.

    1 answer
    1. This product is a Quality level 100. The methods of preparation are proprietary for products with Quality level 100. See the following link for a publication that may be helpful:
      https://www.sciencedirect.com/science/article/pii/S027843431930411X

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