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T3376

Sigma-Aldrich

DL-α-Tocopherol acetate

≥96% (HPLC)

Sinónimos:

Vitamin E acetate, all-rac-α-Tocopheryl acetate

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About This Item

Fórmula empírica (notación de Hill):
C31H52O3
Número de CAS:
7695-91-2
Peso molecular:
472.74
Beilstein:
97512
Número CE:
231-710-0
Número MDL:
MFCD00072042
Código UNSPSC:
12352205
ID de la sustancia en PubChem:
24900133
NACRES:
NA.79
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

synthetic (organic)

Ensayo

≥96% (HPLC)

Formulario

viscous liquid

técnicas

HPLC: suitable

color

colorless to dark yellow

densidad

0.96 g/mL at 20 °C (lit.)

temp. de almacenamiento

2-8°C

cadena SMILES

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

Clave InChI

ZAKOWWREFLAJOT-CEFNRUSXSA-N

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Descripción general

α-Tocopherol is a predominant form of vitamin E in human and animal tissues[1] and also in leaf chloroplasts.[2] It is the major form in supplements.[1] DL-α-Tocopherol acetate is considered as the only storage form of vitamin E.[3]

Aplicación

DL-α-Tocopherol acetate has been used to study it effect on blood pressure and lipidic profile in streptozotocin-induced diabetes mellitus rats.[4] It has also been used as a standard in α-tocopherol analysis using plasma sample[5][6] and mature fresh tobacco leaves.[7]

Acciones bioquímicas o fisiológicas

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

No data available

Punto de inflamabilidad (°C)

No data available

Equipo de protección personal

Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000403089
0000403090
0000380672
0000403090
0000403089

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Nutrient Requirements of Fish and Shrimp (2011)
High levels of dietary unsaturated fat decrease alpha-tocopherol content of whole body, liver, and plasma of chickens without variations in intestinal apparent absorption
Villaverde C, et al.
Poultry Science, 87(3), 497-505 (2008)
Effect of alpha-tocopherol supplementation on blood pressure and lipidic profile in streptozotocin-induced diabetes mellitus in spontaneously hypertensive rats
da Costa VAV and Vianna LM
Clinica Chimica Acta; International Journal of Clinical Chemistry, 351(1-2), 101-104 (2005)
Lowered plasma vitamin C, but not vitamin E, concentrations in dementia patients
Charlton KE, et al.
The Journal of Nutrition, Health & Aging, 8(2), 99-108 (2004)
gamma-Tocopherol, the major form of vitamin E in the US diet, deserves more attention
Jiang Q, et al.
American Journal of Clinical Nutrition, 74(6), 714-722 (2001)
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Artículos

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is the concentration?

    1 answer

    1. This product is a neat or pure liquid and has not been diluted. The concentration may be determined by using the lot specific purity reported in the Certificate of Analysis, the density, and the compound molecular weight. This product has a density of 0.96 g/mL and a molecular weight of 472.74 g/mol. The minimum purity is 96%, thus the molarity will vary slightly from lot to lot. The molarity can range from 1.95M (96%) to 2.03M (100%). Please see the link below to review the product datasheet for additional information.
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/295/556/t3376pis.pdf

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