SRP6092

FKBP1B human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Sinónimos: FKBP12.6, FKBP1L, OTK4, PKBP1IL, Peptidyl prolyl cis-trans isomerase FKBP1B
• UNSPSC Code: 12352204
• NACRES: NA.32

Propiedades

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥90% (SDS-PAGE)
• form: liquid
• mol wt: 14.2 kDa
• packaging: pkg of 100 μg
• NCBI accession no.: P68106
• UniProt accession no.: P68106
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... FKBP1B(2281)

Descripción

General description

Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B) belongs to the immunophilin protein family which has a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP1B is a cis-trans prolyl isomerase which binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). FKBP1B is extremely similar to the FK506-binding protein 1A. The physiological role of FKBP1B is thought to be in excitation-contraction coupling in cardiac muscle.

Physical form

0.25 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 20% glycerol.

Preparation Note

Centrifuge the vial prior to opening.

Other Notes

MGSSHHHHHH SSGLVPRGSH RSMGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL IFDVELLNLE

Información de seguridad

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable