SAB5500139

Anti-MAGE-A1 antibody, Rabbit monoclonal

clone SP188, recombinant, expressed in proprietary host, affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• recombinant: expressed in proprietary host
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: SP188, monoclonal
• species reactivity: human (tested)
• technique(s): flow cytometry: 1:400; immunoblotting: 1:400; immunohistochemistry: 1:100
• isotype: IgG
• UniProt accession no.: P43355
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... MAGEA1(4100)

Descripción

General description

Melanoma-associated antigen 1 (MAGE-A1) is a member of the MAGE family. It is encoded by the gene mapped to human chromosome Xq28.

Melanoma-associated antigen 1 (MAGE-A1) is one of the melanoma associated antigens (MAAs). MAGE-A1 is highly expressed in testis and some human solid tumors such as melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian and renal cell carcinomas.

Immunogen

Synthetic peptide derived from the C-terminus of human MAGE-A1 protein.

Biochem/physiol Actions

Members of MAGE family play a vital role in maintaining normal cellular physiology. Melanoma-associated antigen 1 (MAGE-A1) serves as a target antigen of patient-derived CD8⁺ T cells in melanoma. It might be potential target for treating melanoma patients.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable