SAB4200762

Anti-Opsin antibody, Mouse monoclonal

clone RET-P1, purified from hybridoma cell culture

• Sinónimos: Anti-Opsin 2, Anti-Rhodopsin
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 200
• forma del anticuerpo: purified from hybridoma cell culture
• tipo de anticuerpo: primary antibodies
• clon: RET-P1, monoclonal
• Formulario: buffered aqueous solution
• mol peso: ~39 kDa
• reactividad de especies: avian, bovine, fish, mouse, rat, human, amphibian, turtle, rabbit
• concentración: ~1 mg/mL
• técnicas: ELISA: suitable; immunoblotting: 2-4 μg/mL using human retinoblastoma Y79 cell line extract. ; immunofluorescence: suitable; immunohistochemistry: 5-10 μg/mL using rat eye frozen sections.; radioimmunoassay: suitable
• isotipo: IgG1
• Nº de acceso UniProt: P08100
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: rat ... Rho(24717)

Descripción

Descripción general

Anti-Opsin antibody, Mouse monoclonal (rhodopsin) (mouse IgG1 isotype) is derived from the RET-P1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/C mice immunized with rat retinal membranes. Opsin is also called as rhodopsin protein, members of the G-protein coupled receptor (GPCR) superfamily. Opsin comprises >95% of the rod outer segments (ROS) intrinsic membrane and consists of a protein moiety - an opsin - and a non-protein moiety - the chromophore retinal.

Aplicación

Anti-Opsin antibody has been used in

• immunoblotting
• immunofluorescence
• immunohistochemistry
• enzyme linked immunosorbent assay (ELISA)
• radioimmuno assay (RIA)

Acciones bioquímicas o fisiológicas

Opsin is an essential molecules for mediating the ability of animals to detect and use light for diverse biological functions. Mutations in the opsin (rhodopsin) gene are linked to retinitis pigmentosa (RP), a disease characterized by retinal degeneration resulting in reduced peripheral vision and night blindness.

Otras notas

rat retinal membranes

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable