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Merck

RAB0332

Sigma-Aldrich

Human Lipocalin-2 / NGAL ELISA Kit

for serum, plasma, cell culture supernatant and urine

Sinónimos:

Lipocalin-2, NGAL, Neutrophil gelatinase-associated lipocalin 

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reactividad de especies

human

envase

kit of 96 wells (12 strips x 8 wells)

técnicas

ELISA: suitable
capture ELISA: suitable

entrada

sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 4.1-1000 pg/mL

método de detección

colorimetric

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

Información sobre el gen

human ... LCN2(3934)

Descripción general

Lipocalin-2 (LCN2), a secreted glycoprotein, is an adipokine. It is expressed in various cells like respiratory cells, intestinal epithelial cells, endothelial cells, renal tubular cells and cardiomyocytes. The gene LCN2 is located on human chromosome 9q34. The human lipocalin-2 ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human lipocalin-2 in serum, plasma, cell culture supernatants and urine.

Inmunógeno

Recombinant Human Lipocalin-2

Aplicación

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Lipocalin-2/NGAL ELISA Kit has been used in the electrochemical immunoassay. It has also been used to determine the neutrophil gelatinase-associated lipocalin (NGAL) levels in the urine.

Acciones bioquímicas o fisiológicas

Lipocalin-2 (LCN2) has been implicated in a variety of processes including cell differentiation, tumorigenesis and apoptosis. Polymorphisms in the expression of LCN2 are associated with many cancers such as breast, colorectal, pancreatic, ovarian, gastric, thyroid, ovarian, bladder and kidney cancers.

Otras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Met. Corr. 1

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials


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Visite la Librería de documentos

Kanokporn Pinyopornpanish et al.
Scientific reports, 12(1), 4635-4635 (2022-03-19)
The association between Lipocalin-2 (LCN2) and cognition in patients with metabolic syndrome (MetS) has not been thoroughly investigated. We aimed to evaluate whether serum LCN2 levels are associated with the alteration of cognitive function in patients with MetS. The total
Lipocalin 2, the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion.
Gaudineau B, et. al.
Journal of Cell Science, 125, 4475-4475 (2012)
Ai-Li Sun et al.
Mikrochimica acta, 187(9), 485-485 (2020-08-07)
An innovative signal-transduction tag based on cross-linked urease nanoparticles (CLENP) was designed for the development of a pH meter-based immunoassay of lipocalin-2 (LCN2). The CLENP was synthesized with a typical desolvation method using ethanol as desolvation agent, followed by functionalization with polyaspartic
Julio Cezar Q Machado et al.
Journal of physical activity & health, 15(9), 679-682 (2018-08-03)
Neutrophil gelatinase-associated lipocalin (NGAL) is a glycoprotein released during early phases of a postischemic kidney in response to kidney injury, inflammation, and oxidative stress. It can be detected in urine after 2 hours of an ischemic event. The aim was
Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?
McLean MH
British Journal of Cancer, 108, 2537-2537 (2013)

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