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P9511

Sigma-Aldrich

3-sn-Phosphatidic acid sodium salt from egg yolk lecithin

≥98%

Sinónimos:

1,2-Diacyl-sn-glycero-3-phosphate sodium salt, L-α-Phosphatidic acid sodium salt, PA

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About This Item

Número MDL:
MFCD00063023
Código UNSPSC:
12352106
ID de la sustancia en PubChem:
329820351
NACRES:
NA.77
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Nivel de calidad

200

Ensayo

≥98%

Formulario

powder

temp. de almacenamiento

−20°C

cadena SMILES

[Na+].[Na+].OC[C@@H](O)COP([O-])([O-])=O

InChI

1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;/q;2*+1/p-2/t3-;;/m1../s1

Clave InChI

GEKBIENFFVFKRG-HWYNEVGZSA-L

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Descripción general

Phosphatidic acid is obtained from phosphatidylcholine with the help of phospholipase D.[1]

Aplicación

3-sn-Phosphatidic acid sodium salt from egg yolk lecithin
  • in the reaction mixture for CDS (cytidine triphosphate:phosphatidate cytidyltransferase) assay and reference lipid for thin layer chromatography (TLC)[2]
  • as a standard to compare the generated radiolabeled phosphatidic acid (PA)[3]
  • to examine its effects on At-Rac2–associated kinase activity[4]

Acciones bioquímicas o fisiológicas

Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol, phosphatidic acid and lysophosphatidic acid.[1]

Características y beneficios

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases, Phosphoinositide Kinases and Phosphoprotein Phosphatases (Serine/Threonine) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Nota de preparación

Prepared from L-α-phosphatidylcholine by hydrolysis with cabbage phospholipase D.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000397893
0000397893
0000382347
0000347542
0000347541

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Visite la Librería de documentos

Glycerolipids in signal transduction
Lambeth JD, et al.
New Biotechnology, 31, 237-255 (1996)
Complementary DNAs encoding eukaryotic-type cytidine-5 [prime]-diphosphate-diacylglycerol synthases of two plant species
Kopka J, et al.
Plant Physiology, 113(3), 997-1002 (1997)
Daniel Pastor-Flores et al.
Biochimica et biophysica acta, 1861(3), 249-259 (2016-01-09)
Pkh is the yeast ortholog of the mammalian 3-phosphoinositide-dependent protein kinase 1 (PDK1). Pkh phosphorylates the activation loop of Ypks, Tpks, Sch9 and also phosphorylates the eisosome components Lsp1 and Pil1, which play fundamental roles upstream of diverse signaling pathways
Rac homologues and compartmentalized phosphatidylinositol 4, 5-bisphosphate act in a common pathway to regulate polar pollen tube growth
Kost B, et al.
The Journal of cell biology, 145(2), 317-330 (1999)
Stefano Mancuso et al.
Plant signaling & behavior, 2(4), 240-244 (2007-07-01)
Auxin (IAA) is versatile signalling molecule of plants, currently classified as plant hormone. But there are data suggesting that auxin is acting also as plant-specific morphogen, electric-responses inducing transmitter, and as general signalling molecule used for plant-bacteria communication. Our previous
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