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P3558

Sigma-Aldrich

Paraplast®

for tissue embedding

Sinónimos:

Paraffin – polyisobutylene mixture

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About This Item

Número de CAS:
Número MDL:
Código UNSPSC:
12171500
NACRES:
NA.47
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Nivel de calidad

Formulario

solid

mp

56-57 °C (lit.)
56-57 °C

aplicaciones

hematology
histology

temp. de almacenamiento

room temp

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Descripción general

Paraplast® is a paraffin–polyisobutylene mixture for tissue embedding and infiltration. It is a refined combination of highly purified paraffin with plastic polymers. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.

Aplicación

Paraplast® has been used for tissue embedding and in the following applications:
  • to screen major groups of vertebrates for the presence of cardiac smooth muscle and its phylogenetic distribution in terrestrial and aquatic turtles[1]
  • to study the relationship between membrane impedance and dendrite length of hippocampal neurons[2]
  • to compare the regenerative properties of human stem cells of the apical papilla as an alternative to other dental stem cells[3]

Características y beneficios

  • Minimal tissue compression.
  • Produces wrinkle-free sections.
  • Excellent ribbon continuity.

Otras notas

Double filtered paraffin wax in pellet form.

Información legal

Paraplast is a registered trademark of Leica Biosystems

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Diana B Sequeira et al.
Clinical oral investigations, 25(9), 5317-5329 (2021-02-26)
To compare the regenerative properties of human stem cells of the apical papilla (SCAPs) embedded in a platelet-rich plasma (PRP) scaffold, when implanted in vivo using an organotypic model composed of human root segments, with or without the presence of
Positive Effects of Diphlorethohydroxycarmalol (DPHC) on the Stability of the Integument Structure in Diet-Induced Obese Female Mice
Chae-Lim Kim
Development & reproduction (2015)
Jessica N Witchley et al.
Cell host & microbe, 25(3), 432-443 (2019-03-15)
Candida albicans is a gut commensal and opportunistic pathogen. The transition between yeast and invasive hyphae is central to virulence but has unknown functions during commensal growth. In a mouse model of colonization, yeast and hyphae co-occur throughout the gastrointestinal
Cristina Barrero et al.
Planta, 229(2), 235-247 (2008-10-03)
Transfer cells have specializations that facilitate the transport of solutes across plant exchange surfaces. ZmMRP-1 is a maize (Zea mays) endosperm transfer cell-specific transcriptional activator that plays a central role in the regulatory pathways controlling transfer cell differentiation and function.
Intestinal metabolism of weaned piglets fed a typical United States
or European diet with or without supplementation
of tributyrin and lactitol
A. Piva
Journal of Animal Science (2008)

Contenido relacionado

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Questions

1–2 of 2 Questions  
  1. Is it suitable to use it to cut tissues with implants that have been embedded in Paraplast, Paraplast Xtra, or Paraplast Plus?

    1 answer
    1. Paraplast is commonly used to cut soft tissue to 4 or 5 microns, while Paraplast Xtra can cut down to 2 microns. Paraplast Plus is capable of cutting down to 1 micron, provided the user is skilled; otherwise, slightly thicker sections can be obtained.

      Helpful?

  2. At what temeperature or temperaturintervall the Paraplast is melting?

    1 answer
    1. The Melting point/range is 56-57°C (133-135°F)

      Helpful?

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