N6664

Neurodazine

≥98% (HPLC)

• Sinónimos: 2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H imidazole
• Fórmula empírica (notación de Hill): C₂₇H₂₁ClN₂O₃
• Número de CAS: 937807-66-4
• Peso molecular: 456.92
• MDL number: MFCD08906055
• UNSPSC Code: 12352203
• PubChem Substance ID: 329818668
• NACRES: NA.25

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: yellow
• solubility: DMSO: >20 mg/mL
• storage temp.: −20°C
• SMILES string: COc1ccc(cc1)-c2nc([nH]c2-c3ccc(OC)cc3)-c4ccc(o4)-c5cccc(Cl)c5
• InChI: 1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)
• InChI key: FEEOFPAEDSMOTO-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Neurodazine is a promoter of neurogenesis. It induces a generation of new nerve cells from skeletal muscle fibers both immature, differentiated myotubes and mature skeletal muscle. Neurodazine promotes the expression of neuron-specific markers in treated C2C12 cells (neurogenesis). In addition, in conjunction with a microtubule-destabilizing agent, Neurodazine allows neurogenic conversion of both differentiated immature myotubes and mature skeletal muscle. Neurodazine is a potential alternative approach to using stem cells.

Información de seguridad

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H301,H318,H413
• pcodes: P264 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P405
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Dam. 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges