H8017

Hydroxocobalamin acetate

vitamin B₁₂ analog

• Sinónimos: Vitamin B_12a acetate
• Fórmula empírica (notación de Hill): C₆₄H₉₁CoN₁₃O₁₆P
• Número de CAS: 22465-48-1
• Peso molecular: 1388.39
• Número CE: 245-019-7
• Número MDL: MFCD00082532
• Código UNSPSC: 12352205
• eCl@ss: 34058004
• ID de la sustancia en PubChem: 329815248
• NACRES: NA.79

Propiedades

• origen biológico: synthetic (organic)
• Ensayo: ≥95% (HPLC)
• Formulario: powder
• técnicas: HPLC: suitable
• color: red to brown
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CC(CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N=C1C(C)=C3N=C(C=C4N=C(C(C)=C5[C@@H](CCC(N)=O)[C@](C)(CC(N)=O)[C@@]2(C)N5[Co]OC(C)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78
• InChI: 1S/C62H90N13O14P.C2H4O2.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2(3)4;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3,(H,3,4);/q;;+2/p-3/t31?,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1
• Clave InChI: QHSPIHUMLGFPKX-WYVZQNDMSA-K

Descripción

Descripción general

Hydroxocobalamin is an analog of vitamin B₁₂ with OH as an alkyl group.[1] Vitamin B₁₂ cobalamin refers to a group of chemically-related cobalt containing molecules.[2]

Acciones bioquímicas o fisiológicas

Vitamin B₁₂ cobalamin is involved in DNA synthesis and fatty acid synthesis.[2][3] It also plays a vital role as a coenzyme in the conversion of mitochondrial methylmalonyl co-enzyme A to succinyl co-enzyme A.[2] Vitamin B₁₂ cobalamin is also involved in neurotransmitter synthesis and erythropoiesis. It also functions in the synthesis and maintenance of myelin sheath.[4] Hydroxocobalamin (vitamin B_12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Warning
• Frases de peligro: H351
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Carc. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable