Unfortunately, the purity of this product is not determined by test specifications.
H3884
Hialuronidasa from bovine testes
Type IV-S, lyophilized powder (essentially salt-free), 750-3000 units/mg solid
Sinónimos:
Hialuronato 4-glucanohidrolasa, Hialuronoglucosaminidasa
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About This Item
Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
12352204
NACRES:
NA.54
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
origen biológico
bovine testis
Nivel de calidad
conjugado
conjugate (Glucosaminoglycan)
tpo
Type IV-S
Formulario
lyophilized powder (essentially salt-free)
actividad específica
750-3000 units/mg solid
mol peso
~55 kDa (four subunits of 14 kDa each)
aplicaciones
diagnostic assay manufacturing
enfermedades relevantes
cancer
temp. de almacenamiento
−20°C
Información sobre el gen
cow ... HYAL1(515397) , HYAL2(281838)
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Acciones bioquímicas o fisiológicas
Estas enzimas rompen aleatoriamente los enlaces glucosídicos β-N-acetilhexosamina [1→4] del ácido hialurónico, la condroitina y los sulfatos de condroitina.
La hialuronidasa degrada el hialuronano y se ha observado que su regulación no es apropiada durante la progresión del cáncer.
Definición de unidad
Una unidad degradará 0,75 μg del polisacárido ácido hialurónico por minuto a pH 5,35, a 37 ºC (medido por absorción turbidimétrica (λ: 600 nm) cuando forma complejo con la BSA después de 45 minutos).
Otras notas
Véase más información sobre enzimas para análisis de carbohidratos complejos en www.sigma-aldrich.com/enzymeexplorer
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Resp. Sens. 1
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Certificados de análisis (COA)
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Artículos
Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.
Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.
Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.
Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.
Protocolos
To measure hyaluronidase activity, a turbidimetric determination assay is used at 600 nm. One unit of hyaluronidase activity will cause a change in absorbance of 0.330 per minute at pH 5.35 at 37 °C.
To measure hyaluronidase activity, a turbidimetric determination assay is used at 600 nm. One unit of hyaluronidase activity will cause a change in absorbance of 0.330 per minute at pH 5.35 at 37 °C.
To measure hyaluronidase activity, a turbidimetric determination assay is used at 600 nm. One unit of hyaluronidase activity will cause a change in absorbance of 0.330 per minute at pH 5.35 at 37 °C.
To measure hyaluronidase activity, a turbidimetric determination assay is used at 600 nm. One unit of hyaluronidase activity will cause a change in absorbance of 0.330 per minute at pH 5.35 at 37 °C.
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How pure is the protein?
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How does the storage temperature relate to shipping conditions?
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The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.
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Can stock solutions of Product H3884, Hyaluronidase from bovine testes, be stored frozen after reconstitution?
1 answer-
Although Sigma-Aldrich has not tested the stability of stock solutions of Product H3884, Hyaluronidase from bovine testes, several publications cite storage of solutions of H3884 at -20 °C:1. Campbell, Keith H.S, "Transgenic Sheep form Cultured Cells", from Transgenesis Techniques: Principles and Protocols, Methods Mol. Biol., 180, 289-301 (2002). A 1500 IU/mL stock solution was stored in 20 mL aliquots at -20 °C.2. Marschall, S. and de Angelis, M.H., "In Vitro Fertilization/Cryopreservation", from Transgenic Mouse: Methods and Protocols, Methods in Molecular Biology, 209, pp. 35-50. Humana Press (2003). 1 mg/mL stock solutions in M2 medium or water, sterile-filtered (0.22 mm filter) can be stored in aliquots at -20 °C.
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