GW21181

Anti-VEGFR-2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-Vascular endothelial growth factor receptor 2
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: chicken
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: rat, mouse, human
• manufacturer/tradename: Genway 15-288-21181
• technique(s): immunohistochemistry: suitable; western blot: suitable
• NCBI accession no.: P35968
• UniProt accession no.: P35968
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KDR(3791)

Descripción

Immunogen

Immunogen Sequence: GI # 9087218, sequence 51-119

Recombinant vascular endothelial growth factor receptor 2

Application

Anti-VEGFR-2 antibody produced in chicken is suitable for immunohistochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Kinase insert domain receptor (KDR, a type III receptor tyrosine kinase, VEGFR-2) is a VEGF receptor and is encoded by KDR gene in humans. It plays a crutial role in controlling endothelial trafficking activity and is involved in phosphotyrosine phosphatase 1b (PTP1b). PTP1b acts as a key regulator of endothelial VEGFR2 signaling and plays a critical role in regulation of the extent of vascular tree formation. VEGFR2 may be associated with gout and hyperuricaemia risks in Malays.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)