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Merck

F8399

Sigma-Aldrich

Riboflavin 5′-monphosphate sodium salt hydrate

≥95% (HPLC)

Sinónimos:

FMN

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About This Item

Fórmula empírica (notación de Hill):
C17H20N4O9P · xNa+ · yH2O
Peso molecular:
455.34 (anhydrous free acid basis)
EC Number:
UNSPSC Code:
41106305
eCl@ss:
34058005
NACRES:
NA.51

Quality Level

assay

≥95% (HPLC)

form

powder

storage temp.

−20°C

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General description

Riboflavin 5′-monophosphate (FMN) is highly soluble in water. Flavins are considered as blue-light absorbing dyes.

Application

Riboflavin 5′-monophosphate (FMN) is used as a prosthetic group by oxidoreductase (one and two electron transfer) enzymes such as NADH dehydrogenases, nitric oxide synthases, and nitrilotriacetate monooxygenases. Riboflavin 5′-monophosphate is used as a substrate to study the specificity and kinetics of FMN phosphohydrolases. FMN is used to study molecular sensing based gene regulation by riboswitches.
Riboflavin 5′-monophosphate sodium salt hydrate has been used:
  • in the study to examine FMN (flavin mononucleotide) photo-reduction in aqueous solutions
  • to immobilize on titanium oxide modified carbon fibre to determine its electrochemical behavior
  • in flavin identification

Biochem/physiol Actions

Riboflavin 5′-monophosphate (FMN) acts as a cofactor in flavoproteins and possess biological activity in enzymes and photoreceptors.

Preparation Note

Prepared by the enzymatic hydrolysis of flavin adenine dinucleotide.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

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Visite la Librería de documentos

Delivery of Riboflavin-5?-Monophosphate Into the Cornea: Can Liposomes Provide Any Enhancement Effects?
Kandzija N and Khutoryanskiy VV
Journal of Pharmaceutical Sciences, 106(10), 3041-3049 (2017)
Electrochemical behaviour of FAD and FMN immobilised on TiO2 modified carbon fibres supported by ATR-IR spectroscopy of FMN on TiO2
Kubota LT, et al.
Bioelectrochemistry and bioenergetics, 47(1), 39-46 (1998)
M C Jermy et al.
PloS one, 16(2), e0246123-e0246123 (2021-02-13)
Nasal High Flow (NHF) therapy delivers flows of heated humidified gases up to 60 LPM (litres per minute) via a nasal cannula. Particles of oral/nasal fluid released by patients undergoing NHF therapy may pose a cross-infection risk, which is a
Photo-induced reduction of flavin mononucleotide in aqueous solutions
Song SH, et al.
Chemical Physics, 332(1), 55-65 (2007)
Induction and catalytic properties of an intracellular NADH-dependent 1, 4-benzoquinone reductase from the brown-rot basidiomycete Gloeophyllum trabeum
Qi W and Jellison J
International Biodeterioration & Biodegradation, 54(1), 53-60 (2004)

Artículos

Riboflavin's impact on cell culture systems for manufacturing proteins and monoclonal antibodies discussed.

Riboflavin's impact on cell culture systems for manufacturing proteins and monoclonal antibodies discussed.

Riboflavin's impact on cell culture systems for manufacturing proteins and monoclonal antibodies discussed.

Riboflavin's impact on cell culture systems for manufacturing proteins and monoclonal antibodies discussed.

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