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Key Documents

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D4288

Sigma-Aldrich

Digalacturonic acid

≥85% (HPLC)

Sinónimos:

α-D-GalA-(1→4)-D-GalA

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About This Item

Fórmula empírica (notación de Hill):
C12H18O13
Número de CAS:
5894-59-7
Peso molecular:
370.26
MDL number:
MFCD00079142
UNSPSC Code:
12352201
PubChem Substance ID:
24893853
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

200

assay

≥85% (HPLC)

form

powder

color

white to off-white

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

OC(C=O)C(O)C(OC1OC(C(O)C(O)C1O)C(O)=O)C(O)C(O)=O

InChI

1S/C12H18O13/c13-1-2(14)3(15)8(7(19)10(20)21)24-12-6(18)4(16)5(17)9(25-12)11(22)23/h1-9,12,14-19H,(H,20,21)(H,22,23)

InChI key

SYBQLSSECRIKMJ-UHFFFAOYSA-N

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Application

Digalacturonic acid (DGA), derived in vivo from pectin catabolism, is used for the co-crystallization of enzymes such as proteinase K. It is used in galacturonic acid metabolism research as a substrate to identify, differentiate and characterized endo- and exopolygalacturonase(s) and gluconase(s). DGA is used to study the transport of oligogalacturonides by systems such as the TogMNAB ABC transporter.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

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V Valmeekam et al.
Molecular plant-microbe interactions : MPMI, 14(6), 816-820 (2001-06-02)
The negative regulatory protein ExuR in Erwinia chrysanthemi regulates expression of the galacturonate uptake (exuT) and utilization (uxaA, uxaB, uxaC) genes. We cloned and determined the nucleotide sequence of the exuR gene from E. chrysanthemi EC16. Analysis of the deduced
Lisha Zhang et al.
Fungal genetics and biology : FG & B, 48(10), 990-997 (2011-06-21)
D-galacturonic acid is the most abundant component of pectin, one of the major polysaccharide constituents of plant cell walls. Galacturonic acid potentially is an important carbon source for microorganisms living on (decaying) plant material. A catabolic pathway was proposed in
V E Miamin et al.
Genetika, 40(9), 1187-1193 (2004-11-24)
A mutant that cannot utilize pectin substances of plant cell walls was obtained via insertion of mini-mini-Tn5xylE transposon into the chromosome of phytopathogenic bacteria Erwinia carotovora subsp. atroseptica. The inability of mutant cells to utilize these substrates was caused by
D Wade Abbott et al.
Journal of molecular biology, 368(5), 1215-1222 (2007-04-03)
Family 28 glycoside hydrolases (polygalacturonases) are found in organisms across the plant, fungal and bacterial kingdoms, where they are central to diverse biological functions such as fruit ripening, biomass recycling and plant pathogenesis. The structures of several polygalacturonases have been
Matan Shelomi et al.
Scientific reports, 6, 26388-26388 (2016-05-24)
Genes acquired by horizontal transfer are increasingly being found in animal genomes. Understanding their origin and evolution requires knowledge about the phylogenetic relationships from both source and recipient organisms. We used RNASeq data and respective assembled transcript libraries to trace
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