75632

Osmium tetroxide solution

suitable for electron microscopy, 4% in H₂O

• Sinónimos: Osmium(IV) oxide
• Fórmula lineal: OsO₄
• Número de CAS: 20816-12-0
• Peso molecular: 254.23
• MDL number: MFCD00011150
• UNSPSC Code: 12171500
• PubChem Substance ID: 57652576
• NACRES: NA.47

Propiedades

• form: solution
• Quality Level: 100
• reaction suitability: reagent type: oxidant
• concentration: 4% in H₂O
• technique(s): electron microscopy: suitable
• color: colorless to yellow
• pH: 6.0-8.0
• density: 1.0 g/mL at 20 °C
• application(s): hematology; histology
• storage temp.: 2-8°C
• SMILES string: O=[Os](=O)(=O)=O
• InChI: 1S/4O.Os
• InChI key: VUVGYHUDAICLFK-UHFFFAOYSA-N

Descripción

Application

Osmium tetroxide solution has been used as a fixative in scanning and transmission electron microscopy.

Biochem/physiol Actions

Osmium tetroxide is also referred to as osmium and is mainly used as a secondary fixative of tissues. The molecule reacts with lipid moieties and is responsible for the oxidation of unsaturated bonds of fatty acids. This reaction adds density and contrast to biological samples. In normal tissues, presence of osmium results in intense black staining which can be viewed by normal eye. In addition, it can be used as a mordant (a molecule which combines with stain or dye at later stages) in electron microscopy, thereby enhancing lead staining.

Packaging

5 mL in ampule
10 mL in ampule

Other Notes

Due to the hazardous nature of osmium tetroxide, it is recommended to use an ampule opener when using this chemical.

Información de seguridad

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H302 + H332,H310,H315,H318
• pcodes: P262 - P280 - P301 + P312 - P302 + P352 + P310 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter