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53163

Sigma-Aldrich

Hyaluronic acid sodium salt from Streptococcus equi

mol wt 750,000-1,000,000

Sinónimos:

Sodium hyaluronate

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About This Item

Número de CAS:
9067-32-7
MDL number:
MFCD01773053
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

(Streptococcus equi)

Quality Level

100

form

powder

mol wt

750,000-1,000,000

color

white

solubility

water: ~5 g/L

suitability

conforms to structure for Infrared spectrum

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1

InChI key

YWIVKILSMZOHHF-QJZPQSOGSA-N

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Application

suitable as substrate for hyaluronidase

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Dianhua Jiang et al.
Physiological reviews, 91(1), 221-264 (2011-01-21)
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety of immune cells at the injury site. Hyaluronan binds to a number of cell surface proteins
H Porsch et al.
Oncogene, 32(37), 4355-4365 (2012-10-31)
Epithelial-mesenchymal transition (EMT) is a developmental program, which can be adopted by cancer cells to increase their migration and ability to form metastases. Transforming growth factor β (TGFβ) is a well-studied inducer of EMT. We demonstrate that TGFβ potently stimulates
Melissa R Junttila et al.
Nature, 501(7467), 346-354 (2013-09-21)
Tumour formation involves the co-evolution of neoplastic cells together with extracellular matrix, tumour vasculature and immune cells. Successful outgrowth of tumours and eventual metastasis is not determined solely by genetic alterations in tumour cells, but also by the fitness advantage
J Ye et al.
Eye (London, England), 26(7), 1012-1020 (2012-05-19)
To investigate the toxic effects of ethylenediaminetetraacetic acid disodium salt (EDTA), a corneal penetration enhancer in topical ophthalmic formulations, on DNA in human corneal epithelial cells (HCEs), and to investigate whether the effect induced by EDTA can be inhibited by
Suzhen Zhang et al.
The Journal of biological chemistry, 289(19), 13531-13542 (2014-03-22)
Heavy chain (HC)-hyaluronan (HA), a complex formed by the covalent linkage between HC1 from the inter-α-trypsin inhibitor (IαI) and HA, purified from the human amniotic membrane (AM), is responsible for the anti-inflammatory, antiscarring, and antiangiogenic actions of the AM. This
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