203A-1

Alpha-Fetoprotein Rabbit Polyclonal Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: Ig fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• descripción: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (203A-14); vial of 0.5 mL concentrate (203A-15); bottle of 1.0 mL predilute (203A-17); vial of 1.0 mL concentrate (203A-16); bottle of 7.0 mL predilute (203A-18)
• fabricante / nombre comercial: Cell Marque^®
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• control: fetal liver
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: cytoplasmic

Descripción

Descripción general

Alpha-fetoprotein (AFP) is a fetal tumor-associated polypeptide of the albuminoid gene family that binds and transports molecules in addition to many other proposed functions. This secretory protein is produced by the fetal yolk sac and liver but is found only in trace amounts in adult liver. AFP expression by immunohistochemistry is seen in hepatocellular carcinoma (HCC).
Positive staining with anti-AFP is seen in hepatocytes of the fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a yolk sac carcinoma, or one of a few other tumors. Correspondingly, in conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in yolk sac tumors of gonadal and extragonadal sites, in hepatic malignancies, and in a few other neoplasms. The antigen is not denatured by most fixatives.

Calidad

IVD

IVD

IVD

RUO

Ligadura / enlace

Alpha-Fetoprotein Positive Control Slides, Product No. 203S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

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Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany