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17927

Sigma-Aldrich

9-Oxo-10(9H)-acridineacetic acid

for HPLC derivatization, ≥99.0% (T)

Sinónimos:

(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid, 10-(Carboxymethyl)-9(10H)acridone

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About This Item

Fórmula empírica (notación de Hill):
C15H11NO3
Número de CAS:
38609-97-1
Peso molecular:
253.25
Beilstein/REAXYS Number:
227508
MDL number:
MFCD00157050
UNSPSC Code:
12352106
PubChem Substance ID:
329751585
NACRES:
NA.32

grade

for HPLC derivatization

Quality Level

100

assay

≥99.0% (T)

form

solid

mp

~289 °C (dec.)

SMILES string

OC(=O)CN1c2ccccc2C(=O)c3ccccc13

InChI

1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

InChI key

UOMKBIIXHQIERR-UHFFFAOYSA-N

Application

9-Oxo-10(9H)-acridineacetic acid and its analogs are used to study their potential activity as interferon inducers.

Other Notes

Reagent for pre-column derivatization of amino acids for fluorescent determination in HPLC; Building block in pharmaceutics

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Induction of interferon in mice by sodium salt of 9-oxo-10-acridineacetic acid: specific enhancement by analogs.
Inglot AD, Mlochowski J, Szulc Z, et al.
Arch. Immunol. Ther. Exp., 33, 275-285 (1985)
A A Shul'diakov et al.
Klinicheskaia meditsina, 90(8), 61-63 (2012-10-30)
The aim of the study was to estimate the efficacy of liniment cycloferon included in combined therapy of herpetic infection in 30 patients with psoriasis divided into 2 groups. Combined treatment of patients with recurrent herpetic infection promoted elimination of
E D Bazhanova
Eksperimental'naia i klinicheskaia farmakologiia, 75(7), 40-44 (2012-10-03)
In recent years, both interferons and inductors of endogenous interferon production find increasing use in clinical practice. The latter agents are characterized by high antiviral and immunomodulatory activity in the absence of serious side effects, which makes it possible to
D S Sukhanov et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (1)(1), 65-69 (2013-06-29)
The results of pre-clinical research of cycloferon, remaxol and runihol on the model of experimental generalized tuberculosis, caused by the MBT with a different spectrum of drug sensitivity are presented. A considerable increase of the curative effect of the therapy
A A Shul'diakov et al.
Eksperimental'naia i klinicheskaia farmakologiia, 75(11), 35-37 (2013-01-18)
The efficiency of cycloferon liniment in combined treatment of herpetic infection in patients with latent form of HIV infection has been assess by observations of 40 patients divided into two groups. In the first group, the standard treatment was supplemented
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