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Y0000487

Leflunomide impurity A

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

4-(Trifluoromethyl)aniline, α,α,α-Trifluoro-p-toluidine, 4-Aminobenzotrifluoride

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About This Item

Fórmula lineal:
CF3C6H4NH2
Número de CAS:
455-14-1
Peso molecular:
161.12
Beilstein:
1564853
Número MDL:
MFCD00064396
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329830979
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

pharmaceutical primary standard

familia API

leflunomide

fabricante / nombre comercial

EDQM

índice de refracción

n20/D 1.483 (lit.)

bp

83 °C/12 mmHg (lit.)

densidad

1.283 g/mL at 25 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

Nc1ccc(cc1)C(F)(F)F

InChI

1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2

Clave InChI

ODGIMMLDVSWADK-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Leflunomide impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

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Descripción
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1357045

Leflunomide Related Compound A, United States Pharmacopeia (USP) Reference Standard

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Leflunomide Related Compound B, United States Pharmacopeia (USP) Reference Standard

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Leflunomide Related Compound C, United States Pharmacopeia (USP) Reference Standard

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Leflunomide, Pharmaceutical Secondary Standard; Certified Reference Material

BP1233

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PHR2878

Leflunomide Related Compound B, pharmaceutical secondary standard, certified reference material

Palabra de señalización

Danger

Frases de peligro

H301,H318,H410

Clasificaciones de peligro

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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R E Cilley et al.
Journal of pediatric surgery, 35(1), 113-118 (2000-01-26)
The mechanisms by which static airway pressures in the developing lung affect development are unknown. The in vitro murine fetal lung model with airway ligation reproduces the phenomenon of intraluminal airway pressure in developing lungs. We have applied the technique
H Klein
Biochemistry and cell biology = Biochimie et biologie cellulaire, 75(2), 177-182 (1997-01-01)
A cDNA coding for the hamster S24 ribosomal protein was used to isolate homologous genes from a Syrian hamster fibroblast genomic library. Southern analysis, using S24 ribosomal protein cDNA and two probes derived from the 5' and 3' ends, suggests
V Kruft et al.
Biochimie, 73(7-8), 855-860 (1991-07-01)
The complete amino acid sequences of 3 proteins from the 50S subunit of Bacillus stearothermophilus ribosomes were determined by N-terminal sequence analysis and by sequencing of overlapping fragments obtained from enzymatic digestions and chemical cleavages. The proteins BstL28, BstL33 and
B A Maguire et al.
Molecular microbiology, 23(2), 237-245 (1997-01-01)
Strain BM108 of Escherichia coli has a chromosomal mutation in the rpmB,G operon that prevents synthesis of ribosomal proteins L28 and L33. The mutation was lethal unless synthesis of protein L28 was induced from a plasmid. Without protein L28, RNA
J Seifert et al.
Toxicology, 83(1-3), 49-59 (1993-10-25)
Reactive isomeric 3- and 4-trifluoromethylanilines (3-,4-TFMA), and control aniline itself, induced the following effects on biosynthesis of DNA in the liver, kidney, thymus and spleen of rats: (a) The administration of 4-TFMA initially suppressed the utilization of labeled thymidine for
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