PHR1549

1,4 Dioxano

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Dioxano, Óxido de dietileno
• Fórmula empírica (notación de Hill): C₄H₈O₂
• Número de CAS: 123-91-1
• Peso molecular: 88.11
• Beilstein: 102551
• Número CE: 204-661-8
• Número MDL: MFCD00006571
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823458
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to USP 1601521
• densidad de vapor: 3 (vs air)
• presión de vapor: 27 mmHg ( 20 °C); 40 mmHg ( 25 °C)
• CofA: current certificate can be downloaded
• temp. de autoignición: 356 °F
• lim. expl.: 22 %
• envase: ampule of 3x1.2 mL each
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• índice de refracción: n20/D 1.422 (lit.)
• bp: 100-102 °C (lit.)
• mp: 10-12 °C (lit.)
• densidad: 1.034 g/mL at 25 °C (lit.)
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-30°C
• cadena SMILES: C1COCCO1
• InChI: 1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2
• Clave InChI: RYHBNJHYFVUHQT-UHFFFAOYSA-N

Descripción

Descripción general

1,4-Dioxane belongs to the class of volatile organic compounds (VOCs).[1]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

1,4-Dioxane may be used as a pharmaceutical reference standard for the determination of the analyte in bulk pharmaceuticals, and cosmetic raw materials and finished products by chromatography.[2][3][4]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC0289 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información de seguridad

• Pictogramas: GHS02,GHS08,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H225,H319,H335,H350
• Consejos de prudencia: P202 - P210 - P233 - P240 - P305 + P351 + P338 - P308 + P313
• Clasificaciones de peligro: Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Riesgos supl.: EUH019,EUH066
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 51.8 °F - closed cup
• Punto de inflamabilidad (°C): 11 °C - closed cup