PHR1168
Ofloxacin
Pharmaceutical Secondary Standard; Certified Reference Material
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About This Item
Fórmula empírica (notación de Hill):
C18H20FN3O4
Número de CAS:
Peso molecular:
361.37
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Productos recomendados
grade
certified reference material
pharmaceutical secondary standard
Quality Level
agency
traceable to USP 1478108
API family
ofloxacin, ofloxacin
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
InChI
1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
InChI key
GSDSWSVVBLHKDQ-UHFFFAOYSA-N
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Ofloxacin is an orally administered antimicrobial drug that is classified under the group of fluoroquinolones. It has high potency and shows a broad-spectrum antibacterial performance, as well as short selection of resistant bacteria.
Ofloxacin is an orally administered antimicrobial drug that is classified under the group of fluoroquinolones. It has high potency and shows a broad-spectrum antibacterial performance, as well as short selection of resistant bacteria.
Application
Ofloxacin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and serum samples by chromatography and spectrophotometry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA7180 in the slot below. This is an example certificate only and may not be the lot that you receive.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
related product
Referencia del producto
Descripción
Precios
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Los clientes también vieron
Determination of Ofloxacin in Pharmaceutical Forms by High-Performance Liquid Chromatography and Derivative Uvspectrophotometry
Carlucci G, et al.
Analytical Letters, 26(10), 2193-2201 (1993)
Simultaneous determination of ofloxacin and flavoxate hydrochloride by absorption ratio and second derivative UV spectrophotometry
Attimarad M
Journal of Basic and Clinical Pharmacy, 2(1), 53-53 (2010)
Determination of ofloxacin in tear by HPLC-ESI-MS/MS method: Comparison of ophthalmic drug release between a new mucoadhesive chitosan films and a conventional eye drop formulation in rabbit model
Byrro RMD, et al.
Journal of Pharmaceutical and Biomedical Analysis, 70(5), 544-548 (2012)
Cécile Denève et al.
Antimicrobial agents and chemotherapy, 53(12), 5155-5162 (2009-10-07)
Recent outbreaks of Clostridium difficile infection have been related to the emergence of the NAP1/027 epidemic strain. This strain demonstrates increased virulence and resistance to the C-8-methoxyfluoroquinolones gatifloxacin and moxifloxacin. These antibiotics have been implicated as major C. difficile infection-inducing
Chee Wee Gan et al.
The Laryngoscope, 123(7), 1770-1777 (2013-05-15)
To develop a novel drug-eluting biodegradable ventilation tube (VT), to evaluate in vitro sustained release and antibacterial adherence of ofloxacin-loaded biodegradable VT on Pseudomonas aeruginosa, and to evaluate in vivo biodegradation of VT in guinea pig ears. A randomized animal
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