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I0375000

Isoconazole

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole

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About This Item

Fórmula empírica (notación de Hill):
C18H14Cl4N2O
Número de CAS:
27523-40-6
Peso molecular:
416.13
Código UNSPSC:
41116107
NACRES:
NA.24
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grado

pharmaceutical primary standard

familia API

isoconazole

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

Clc1c(c(ccc1)Cl)COC(C[n]3cncc3)c2c(cc(cc2)Cl)Cl

InChI

1S/C18H14Cl4N2O/c19-12-4-5-13(17(22)8-12)18(9-24-7-6-23-11-24)25-10-14-15(20)2-1-3-16(14)21/h1-8,11,18H,9-10H2

Clave InChI

MPIPASJGOJYODL-UHFFFAOYSA-N

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Isoconazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Marcus Henrique de S B Xavier et al.
Dermatology online journal, 14(8), 15-15 (2008-12-09)
Tinea nigra is an asymptomatic superficial fungal infection caused by Phaeoannelomyces werneckii, generally affecting the skin of the palms and characterized by deeply pigmented macular non-scaly patches. These lesions are quite characteristic. However, they can be misdiagnosed as a malignant
Tinea cruris treated with a combined topical therapy containing isoconazole and a corticosteroid.
Jaco Jürgens
Mycoses, 51 Suppl 4, 32-33 (2008-09-12)
J Lademann et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80(3), 615-620 (2012-01-31)
Bacteria and fungi are located in the stratum corneum and the hair follicles. Therefore, the development and assessment of efficient drugs requires standard in vivo investigation methods permitting a differentiation between intercellular and follicular penetration and storage of topically applied
Treatment of candidal intertrigo with a topical combination of isoconazole nitrate and diflucortolone valerate.
Bilal Dogan et al.
Mycoses, 51 Suppl 4, 42-43 (2008-09-12)
Blanka Havlickova et al.
Mycoses, 51 Suppl 4, 16-26 (2008-09-12)
Dermatomycoses are contagious superficial fungal infections, which are highly prevalent in developed and developing countries. Caused by a range of Epidermophyton, Microsporum and Trichophyton species, dermatomycoses manifest on glabrous skin as 'ringworm', an annular scaly lesion with a variable inflammatory
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