90281

Andrographolide

analytical standard

• Sinónimos: (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone, ent-(3β,12E,14R)-3,14,19-Trihydroxy-8(17),12-labdadien-16,15-olide, Andrographis
• Fórmula empírica (notación de Hill): C₂₀H₃₀O₅
• Número de CAS: 5508-58-7
• Peso molecular: 350.45
• Número CE: 226-852-5
• Número MDL: MFCD07778082
• Código UNSPSC: 85151701
• ID de la sustancia en PubChem: 329769897
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• Ensayo: ≥95% (HPLC)
• caducidad: limited shelf life, expiry date on the label
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: food and beverages
• Formato: neat
• cadena SMILES: C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C\C=C3/[C@H](O)COC3=O)C(=C)CC[C@H]12
• InChI: 1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1
• Clave InChI: BOJKULTULYSRAS-OTESTREVSA-N

Descripción

Descripción general

Andrographolide is a major bioactive component of Andrographis paniculata Nees. which is a popular Chinese and Indian medicine. It belongs to the terpenoid class of compounds.

Aplicación

Andrographolide may be used as a reference standard for the determination of andrographolide in:

• Leaves of Andrographis paniculata by soxhlet extraction-recrystallization-column chromatography purification followed by analyses using reversed phase high performance liquid chromatography (RP-HPLC) as well as gas chromatography-mass spectrometry (GC-MS).
• Roots of Andrographis paniculata by HPLC with diode array detection (DAD), gas chromatography-mass spectrometry (GC-MS) and LC coupled to tandem mass spectrometry (MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode of detection.
• Stems of Andrographis paniculata by ultra-HPLC combined coupled to triple quadrupole-linear ion trap mass spectrometry (QqQ_LIT-ESI-MS/MS) with MRM detection.
• Rat plasma samples by protein precipitation and subsequent ESI-LC-MS/MS determination using MRM detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable