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Merck

90210

Millipore

D-(+)- Trealosa dihydrate

suitable for microbiology, ≥99.0%, composed of two α-glucose units that is used as a protectant, stabilizer and to support proper folding

Sinónimos:

α,α-Trealosa, α-D-Glucopiranosil-α-D-glucopiranósido

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About This Item

Fórmula empírica (notación de Hill):
C12H22O11 · 2H2O
Número de CAS:
Peso molecular:
378.33
Beilstein:
5322018
Número CE:
Número MDL:
Código UNSPSC:
41106212
ID de la sustancia en PubChem:
NACRES:
NA.85

Nivel de calidad

Ensayo

≥99.0% (HPLC)
≥99.0%

Formulario

powder

actividad óptica

[α]20/D +176 to +186°, c = 2% in H2O

mol peso

378.33  g/mol

impurezas

≤0.1% glucose

residuo de ign.

≤0.1% (as SO4)

solubilidad

H2O: 0.1 g/mL, clear, colorless

trazas de anión

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

trazas de catión

As: ≤0.1 mg/kg
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

aplicaciones

microbiology

cadena SMILES

[H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

Clave InChI

DPVHGFAJLZWDOC-PVXXTIHASA-N

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Descripción general

D-(+)-Trehalose is a disaccharide composed of two α-glucose units. It is used as a cryoprotectant in a variety of cell freezing media. Used as a protectant in transportation media. It predominantly exists among the species that support anhydrobiosis (life without water). It serves as a carbohydrate reserve in microorganisms and protects them from adverse conditions, such as heat, cold, dehydration, desiccation, and oxidation. Trehalose acts as a chemical chaperone affecting protein folding. It is known to prevent the generation of amyloids and accumulation of β-amyloid in vitro. A similar effect of trehalose has been observed with Huntingtin protein aggregation. Thus, it might serve as a protective agent in Alzheimer′s disease and Huntington′s disease. Trehalose stimulates the better initial growth of Salmonella cells.

Aplicación

D-(+)-Trehalose can be used as a carbohydrate reserve in certain cell cultures to tide over environmental stresses. It can also be used in biopharmaceutical monoclonal antibody formulations and as a protein stabilizer.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Artículos

Culture media provides a habitat with suitable nutrients, energy sources, and certain environmental conditions for the growth of microorganisms. The components of the culture media range from simple sugars to peptones, salts, antibiotics, and complex indicators.

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