Saltar al contenido
Merck
Todas las fotos(2)

Documentos

77626

Supelco

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

for GC derivatization, LiChropur™, ≥98.0% (GC)

Sinónimos:

MTBSTFA

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(2)

About This Item

Fórmula lineal:
CF3CON(CH3)Si(CH3)2C(CH3)3
Número de CAS:
77377-52-7
Peso molecular:
241.33
Beilstein/REAXYS Number:
3606546
MDL number:
MFCD00009671
UNSPSC Code:
12352111
NACRES:
NA.22

grade

for GC derivatization

assay

≥98.0% (GC)

form

liquid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.402 (lit.)

bp

172-175 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

Storage temp.

2-8°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C

InChI

1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3

Inchi Key

QRKUHYFDBWGLHJ-UHFFFAOYSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

General description

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a silylating reagent which replaces the active hydrogen with tert-Butyldimethylsilyl group. The tert-Butyldimethylsilyl derivatives are found to be more resistant to hydrolysis and stable compared to trimethylsilyl (TMS) derivatives. This reagent is suitable for GC-MS analysis since it produces mass spectra, which can be easily interpreted. It is widely used for the silylation of different alcohols, thiols, phenols, carboxylic acids, amines, and amides.

Application

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide may be used as a derivatizing reagent for the determination of methionine sulfoxide and methionine in blood plasma and chlorpyrifos, diazinon and their major metabolites in sludge and sludge-fertilized agricultural soils using gas-chromatography coupled to mass spectrometry technique.

Recommended products

Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

related product

Referencia del producto
Descripción
Precios

394882

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide, >97%

190500

tert-Butyldimethylsilyl chloride, reagent grade, 97%

375934

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane, ≥95%

473464

tert-Butylchlorodimethylsilane solution, 50 wt. % in toluene

384429

tert-Butyldimethylsilyl chloride solution, 1.0 M in methylene chloride

372951

tert-Butyldimethylsilyl chloride solution, 1.0 M in THF

226149

tert-Butyldimethylsilyl trifluoromethanesulfonate, reagent grade, 98%

250236

1-(tert-Butyldimethylsilyl)imidazole, ≥95%

06735

tert-Butyldimethylsilyl chloride, for GC derivatization, LiChropur™, ≥99.0% (GC)

56563

tert-Butyldimethylsilyl trifluoromethanesulfonate, for GC derivatization, LiChropur™, ≥98.0% (T)

00942

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane, for GC derivatization, LiChropur™, ≥95.0% (GC)

44795

N,O-Bis(tert-butyldimethylsilyl)acetamide, for GC derivatization, LiChropur™, ≥98.0% (GC)

Pictograms

Flame
GHS02

signalword

Warning

hcodes

H226

Hazard Classifications

Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

113.0 °F - closed cup

flash_point_c

45 °C - closed cup

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
BCCL5595
BCCK4857
BCCK1127
BCCH9690
BCCG8319

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Advanced Gas Chromatography: Progress in Agricultural, Biomedical and Industrial Applications (2012)
Highly selective sample preparation and gas chromatographic?mass spectrometric analysis of chlorpyrifos, diazinon and their major metabolites in sludge and sludge-fertilized agricultural soils
Diaz-Cruz SM and Barcelo D
Journal of Chromatography A, 1132(1-2), 21-27 (2006)
Two stage derivatization with N-(tert.-butyldimethylsilyl)-N-methyl-trifluoroacetamide (MTBSTFA) and N-methyl-bis-(trifluoroacetamide)(MBTFA) for the gas-chromatographic analysis of OH-, SH-and NH-compounds
Schoene K, et al.
Fresenius Journal of Analytical Chemistry, 348(5-6), 364-370 (1994)
Ryuichi Mashima et al.
Analytical biochemistry, 313(1), 28-33 (2003-02-11)
Methionine sulfoxide is an oxidation product of methionine with reactive oxygen species via 2-electron-dependent mechanism. Such oxidants can be generated from activated neutrophils; therefore, methionine sulfoxide can be regarded as a biomarker of oxidative stress in vivo. We describe here

Artículos

Silylation of Non-Steroidal Anti-Inflammatory Drugs

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Silylation of Non-Steroidal Anti-Inflammatory Drugs

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Silylation of Non-Steroidal Anti-Inflammatory Drugs

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Silylation of Non-Steroidal Anti-Inflammatory Drugs

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico